Crystal Structure of Pla L 1 Reveals Both Structural Similarity and Allergenic Divergence Within the Ole E 1-like Protein Family

Overview

Journal J Allergy Clin Immunol

Specialty Allergy & Immunology

Date 2016 Dec 15

PMID 27965108

Citations 9

Authors

Teresa Stemeseder

Regina Freier

Sabrina Wildner

Julian E Fuchs

Peter Briza

Roland Lang

Eva Batanero

Jonas Lidholm

Klaus R Liedl

Paloma Campo

Thomas Hawranek

Mayte Villalba

Hans Brandstetter

Fatima Ferreira

Gabriele Gadermaier

Affiliations

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Citing Articles

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Can Physicochemical Properties Alter the Potency of Aeroallergens? Part 1 - Aeroallergen Protein Families.

Teixeira C, Carrico-Sa B, Villa C, Mafra I, Costa J Curr Allergy Asthma Rep. 2024; 24(11):591-607.

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Malnutrition and Allergies: Tipping the Immune Balance towards Health.

Vassilopoulou E, Venter C, Roth-Walter F J Clin Med. 2024; 13(16).

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To stay or not to stay intact as an allergen: the endolysosomal degradation assay used as tool to analyze protein immunogenicity and cell epitopes.

Oztemiz Topcu E, Gadermaier G Front Allergy. 2024; 5:1440360.

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A systematic review of allergen cross-reactivity: Translating basic concepts into clinical relevance.

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References

Calabozo B, Barber D, Polo F . Purification and characterization of the main allergen of Plantago lanceolata pollen, Pla l 1. Clin Exp Allergy. 2001; 31(2):322-30. DOI: 10.1046/j.1365-2222.2001.00985.x. View

Gonzalez E, Villalba M, Quiralte J, Batanero E, Roncal F, Albar J . Analysis of IgE and IgG B-cell immunodominant regions of Ole e 1, the main allergen from olive pollen. Mol Immunol. 2005; 43(6):570-8. DOI: 10.1016/j.molimm.2005.04.015. View

Marazuela E, Hajek R, Villalba M, Barber D, Breiteneder H, Rodriguez R . A non-allergenic Ole e 1-like protein from birch pollen as a tool to design hypoallergenic vaccine candidates. Mol Immunol. 2012; 50(1-2):83-90. DOI: 10.1016/j.molimm.2011.12.006. View

Castro A, Alche J, Calabozo B, Rodriguez-Garcia M, Polo F . Pla 1 1 and Ole e 1 pollen allergens share common epitopes and similar ultrastructural localization. J Investig Allergol Clin Immunol. 2007; 17 Suppl 1:41-7. View

Barderas R, Purohit A, Papanikolaou I, Rodriguez R, Pauli G, Villalba M . Cloning, expression, and clinical significance of the major allergen from ash pollen, Fra e 1. J Allergy Clin Immunol. 2005; 115(2):351-7. DOI: 10.1016/j.jaci.2004.10.001. View