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Marine Organisms with Anti-Diabetes Properties

Overview
Journal Mar Drugs
Publisher MDPI
Specialties Biology
Pharmacology
Date 2016 Dec 6
PMID 27916864
Citations 37
Authors
Affiliations
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Abstract

Diabetes is a chronic degenerative metabolic disease with high morbidity and mortality rates caused by its complications. In recent years, there has been a growing interest in looking for new bioactive compounds to treat this disease, including metabolites of marine origin. Several aquatic organisms have been screened to evaluate their possible anti-diabetes activities, such as bacteria, microalgae, macroalgae, seagrasses, sponges, corals, sea anemones, fish, salmon skin, a shark fusion protein as well as fish and shellfish wastes. Both in vitro and in vivo screenings have been used to test anti-hyperglycemic and anti-diabetic activities of marine organisms. This review summarizes recent discoveries in anti-diabetes properties of several marine organisms as well as marine wastes, existing patents and possible future research directions in this field.

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References
1.
Romano G, Costantini M, Sansone C, Lauritano C, Ruocco N, Ianora A . Marine microorganisms as a promising and sustainable source of bioactive molecules. Mar Environ Res. 2016; 128:58-69. DOI: 10.1016/j.marenvres.2016.05.002. View

2.
Sonksen P, Sonksen J . Insulin: understanding its action in health and disease. Br J Anaesth. 2000; 85(1):69-79. DOI: 10.1093/bja/85.1.69. View

3.
Gokce G, Haznedaroglu M . Evaluation of antidiabetic, antioxidant and vasoprotective effects of Posidonia oceanica extract. J Ethnopharmacol. 2007; 115(1):122-30. DOI: 10.1016/j.jep.2007.09.016. View

4.
Nakao Y, Uehara T, Matsunaga S, Fusetani N, Soest R, Matunaga S . Callyspongynic acid, a polyacetylenic acid which inhibits alpha-glucosidase, from the marine sponge Callyspongia truncata. J Nat Prod. 2002; 65(6):922-4. DOI: 10.1021/np0106642. View

5.
Reimann M, Bonifacio E, Solimena M, Schwarz P, Ludwig B, Hanefeld M . An update on preventive and regenerative therapies in diabetes mellitus. Pharmacol Ther. 2009; 121(3):317-31. DOI: 10.1016/j.pharmthera.2008.11.009. View