Stem Cells and Interspecies Chimaeras

Overview

Journal Nature

Specialty Science

Date 2016 Dec 2

PMID 27905428

Citations 81

Authors

Jun Wu

Henry T Greely

Rudolf Jaenisch

Hiromitsu Nakauchi

Janet Rossant

Juan Carlos Izpisua Belmonte

Affiliations

Soon will be listed here.

Abstract

Chimaeras are both monsters of the ancient imagination and a long-established research tool. Recent advances, particularly those dealing with the identification and generation of various kinds of stem cells, have broadened the repertoire and utility of mammalian interspecies chimaeras and carved out new paths towards understanding fundamental biology as well as potential clinical applications.

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