Self-reported Mobile Phone Use and Semen Parameters Among Men from a Fertility Clinic

Overview

Journal Reprod Toxicol

Specialties Reproductive Medicine
Toxicology

Date 2016 Nov 14

PMID 27838386

Citations 8

Authors

Ryan C Lewis

Lidia Minguez-Alarcon

John D Meeker

Paige L Williams

Gabor Mezei

Jennifer B Ford

Russ Hauser

Affiliations

Soon will be listed here.

Abstract

There is increasing concern that use of mobile phones, a source of low-level radio-frequency electromagnetic fields, may be associated with poor semen quality, but the epidemiologic evidence is limited and conflicting. The relationship between mobile phone use patterns and markers of semen quality was explored in a longitudinal cohort study of 153 men that attended an academic fertility clinic in Boston, Massachusetts. Information on mobile phone use duration, headset or earpiece use, and the body location in which the mobile phone was carried was ascertained via nurse-administered questionnaire. Semen samples (n=350) were collected and analyzed onsite. To account for multiple semen samples per man, linear mixed models with random intercepts were used to investigate the association between mobile phone use and semen parameters. Overall, there was no evidence for a relationship between mobile phone use and semen quality.

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References

Yan J, Agresti M, Bruce T, Yan Y, Granlund A, Matloub H . Effects of cellular phone emissions on sperm motility in rats. Fertil Steril. 2007; 88(4):957-64. DOI: 10.1016/j.fertnstert.2006.12.022. View

Eisenberg M, Chen Z, Ye A, Buck Louis G . Relationship between physical occupational exposures and health on semen quality: data from the Longitudinal Investigation of Fertility and the Environment (LIFE) Study. Fertil Steril. 2015; 103(5):1271-7. PMC: 4417418. DOI: 10.1016/j.fertnstert.2015.02.010. View

Meeker J, Ehrlich S, Toth T, Wright D, Calafat A, Trisini A . Semen quality and sperm DNA damage in relation to urinary bisphenol A among men from an infertility clinic. Reprod Toxicol. 2010; 30(4):532-9. PMC: 2993767. DOI: 10.1016/j.reprotox.2010.07.005. View

Gollenberg A, Liu F, Brazil C, Drobnis E, Guzick D, Overstreet J . Semen quality in fertile men in relation to psychosocial stress. Fertil Steril. 2009; 93(4):1104-11. DOI: 10.1016/j.fertnstert.2008.12.018. View

Cooper T, Noonan E, von Eckardstein S, Auger J, Baker H, Behre H . World Health Organization reference values for human semen characteristics. Hum Reprod Update. 2009; 16(3):231-45. DOI: 10.1093/humupd/dmp048. View

La Vignera S, Condorelli R, Vicari E, DAgata R, Calogero A . Effects of the exposure to mobile phones on male reproduction: a review of the literature. J Androl. 2011; 33(3):350-6. DOI: 10.2164/jandrol.111.014373. View

Dasdag S, Ketani M, Akdag Z, Ersay A, Sari I, Demirtas O . Whole-body microwave exposure emitted by cellular phones and testicular function of rats. Urol Res. 1999; 27(3):219-23. DOI: 10.1007/s002400050113. View

Travison T, Araujo A, Hall S, McKinlay J . Temporal trends in testosterone levels and treatment in older men. Curr Opin Endocrinol Diabetes Obes. 2009; 16(3):211-7. DOI: 10.1097/med.0b013e32832b6348. View

Lee H, Pack J, Kim T, Kim N, Choi S, Lee J . The lack of histological changes of CDMA cellular phone-based radio frequency on rat testis. Bioelectromagnetics. 2010; 31(7):528-34. DOI: 10.1002/bem.20589. View

10.

Zhang M, Shi Z, Yu J, Zhang Y, Wang L, Qiu Y . Scrotal heat stress causes sperm chromatin damage and cysteinyl aspartate-spicific proteinases 3 changes in fertile men. J Assist Reprod Genet. 2015; 32(5):747-55. PMC: 4429437. DOI: 10.1007/s10815-015-0451-0. View

11.

Cutillas-Tolin A, Minguez-Alarcon L, Mendiola J, Lopez-Espin J, Jorgensen N, Navarrete-Munoz E . Mediterranean and western dietary patterns are related to markers of testicular function among healthy men. Hum Reprod. 2015; 30(12):2945-55. PMC: 4643528. DOI: 10.1093/humrep/dev236. View

12.

Swan S, Elkin E, Fenster L . Have sperm densities declined? A reanalysis of global trend data. Environ Health Perspect. 1998; 105(11):1228-32. PMC: 1470335. DOI: 10.1289/ehp.971051228. View

13.

Agarwal A, Deepinder F, Sharma R, Ranga G, Li J . Effect of cell phone usage on semen analysis in men attending infertility clinic: an observational study. Fertil Steril. 2007; 89(1):124-8. DOI: 10.1016/j.fertnstert.2007.01.166. View

14.

Carlsen E, Giwercman A, Keiding N, Skakkebaek N . Evidence for decreasing quality of semen during past 50 years. BMJ. 1992; 305(6854):609-13. PMC: 1883354. DOI: 10.1136/bmj.305.6854.609. View

15.

Rago R, Salacone P, Caponecchia L, Sebastianelli A, Marcucci I, Calogero A . The semen quality of the mobile phone users. J Endocrinol Invest. 2013; 36(11):970-4. DOI: 10.3275/8996. View

16.

Fejes I, Zavaczki Z, Szollosi J, Koloszar S, Daru J, Kovacs L . Is there a relationship between cell phone use and semen quality?. Arch Androl. 2005; 51(5):385-93. DOI: 10.1080/014850190924520. View

17.

Swan S, Elkin E, Fenster L . The question of declining sperm density revisited: an analysis of 101 studies published 1934-1996. Environ Health Perspect. 2000; 108(10):961-6. PMC: 1240129. DOI: 10.1289/ehp.00108961. View

18.

Meeker J, Yang T, Ye X, Calafat A, Hauser R . Urinary concentrations of parabens and serum hormone levels, semen quality parameters, and sperm DNA damage. Environ Health Perspect. 2010; 119(2):252-7. PMC: 3040614. DOI: 10.1289/ehp.1002238. View

19.

Tokola K, Kurttio P, Salminen T, Auvinen A . Reducing overestimation in reported mobile phone use associated with epidemiological studies. Bioelectromagnetics. 2008; 29(7):559-63. DOI: 10.1002/bem.20424. View

20.

Minguez-Alarcon L, Chavarro J, Mendiola J, Gaskins A, Torres-Cantero A . Physical activity is not related to semen quality in young healthy men. Fertil Steril. 2014; 102(4):1103-9. PMC: 4393647. DOI: 10.1016/j.fertnstert.2014.06.032. View