Development of Stimulus Material for Research in Alcohol Use Disorders

Overview

Journal Int J Methods Psychiatr Res

Specialty Psychiatry

Date 2016 Oct 13

PMID 27730743

Citations 7

Authors

Werner Fey

Franz Moggi

Kristina B Rohde

Chantal Michel

Andrea Seitz

Maria Stein

Affiliations

Soon will be listed here.

Abstract

The availability of appropriate stimulus material is a key concern for an experimental approach to research on alcohol use disorders (AUDs). A large number of such stimuli are necessary to evoke relevant alcohol-related associations. We report the development of a large stimulus database consisting of 457 pictures of alcoholic beverages and 398 pictures of neutral objects. These stimuli were rated by 18 inpatients hospitalized due to severe AUD and 18 healthy controls along four dimensions: arousal, valence, alcohol-relatedness, and craving. Physical parameters of the pictures were assessed. After outlier removal, 831 stimuli that were characterized as either alcohol-related or neutral were retained in the final stimulus pool. Alcohol-related pictures (versus neutral pictures) evoked higher arousal, more craving and were judged to have higher alcohol-relatedness and a more negative valence. Group comparisons indicated that in patients, neutral pictures evoked more craving and had higher alcohol-relatedness than they did in controls. Physical parameters such as visual complexity, luminance, and color were extracted from these pictures, and extreme values were normalized to minimize mean differences between alcoholic and neutral stimuli. The pictures met the qualitative requirements for (neurophysiological) research. A data file containing rating values and physical parameters will be provided upon request.

Citing Articles

Positive affect amplifies integration within episodic memories in the laboratory and the real world.

Pratt J, Wemm S, Harris B, Huang Y, Sinha R, Goldfarb E Learn Mem. 2025; 32(1).

PMID: 39870487 PMC: 11801478. DOI: 10.1101/lm.053971.124.

Hippocampal Mechanisms Support Cortisol-Induced Memory Enhancements.

Sherman B, Harris B, Turk-Browne N, Sinha R, Goldfarb E J Neurosci. 2023; 43(43):7198-7212.

PMID: 37813570 PMC: 10601369. DOI: 10.1523/JNEUROSCI.0916-23.2023.

Pictures Library of Smoking Cravings: Development and Verification of Smokers and Non-smokers.

Gu Z, Zheng H, Yin Z, Cai H, Li Y, Zhao C Front Psychiatry. 2021; 12:719782.

PMID: 34484007 PMC: 8415710. DOI: 10.3389/fpsyt.2021.719782.

Evidence for incentive salience sensitization as a pathway to alcohol use disorder.

Cofresi R, Bartholow B, Piasecki T Neurosci Biobehav Rev. 2019; 107:897-926.

PMID: 31672617 PMC: 6878895. DOI: 10.1016/j.neubiorev.2019.10.009.

Wake Forest Alcohol Imagery Set: Development and Validation of a Large Standardized Alcohol Imagery Dataset.

Peterson H, Simpson S, Laurienti P Alcohol Clin Exp Res. 2019; 43(12):2559-2567.

PMID: 31595975 PMC: 6904540. DOI: 10.1111/acer.14214.

References

Wrase J, Grusser S, Klein S, Diener C, Hermann D, Flor H . Development of alcohol-associated cues and cue-induced brain activation in alcoholics. Eur Psychiatry. 2002; 17(5):287-91. DOI: 10.1016/s0924-9338(02)00676-4. View

Miller M, Fillmore M . The effect of image complexity on attentional bias towards alcohol-related images in adult drinkers. Addiction. 2010; 105(5):883-90. PMC: 2922935. DOI: 10.1111/j.1360-0443.2009.02860.x. View

Ihssen N, Cox W, Wiggett A, Fadardi J, Linden D . Differentiating heavy from light drinkers by neural responses to visual alcohol cues and other motivational stimuli. Cereb Cortex. 2010; 21(6):1408-15. DOI: 10.1093/cercor/bhq220. View

Bradley M, Hamby S, Low A, Lang P . Brain potentials in perception: picture complexity and emotional arousal. Psychophysiology. 2007; 44(3):364-73. DOI: 10.1111/j.1469-8986.2007.00520.x. View

Wiers R, Bartholow B, Van Den Wildenberg E, Thush C, Engels R, Sher K . Automatic and controlled processes and the development of addictive behaviors in adolescents: a review and a model. Pharmacol Biochem Behav. 2006; 86(2):263-83. DOI: 10.1016/j.pbb.2006.09.021. View

Kreusch F, Vilenne A, Quertemont E . Response inhibition toward alcohol-related cues using an alcohol go/no-go task in problem and non-problem drinkers. Addict Behav. 2013; 38(10):2520-8. DOI: 10.1016/j.addbeh.2013.04.007. View

Dickter C, Forestell C, Hammett P, Young C . Relationship between alcohol dependence, escape drinking, and early neural attention to alcohol-related cues. Psychopharmacology (Berl). 2013; 231(9):2031-40. PMC: 3988240. DOI: 10.1007/s00213-013-3348-6. View

Pronk T, van Deursen D, Beraha E, Larsen H, Wiers R . Validation of the Amsterdam Beverage Picture Set: A Controlled Picture Set for Cognitive Bias Measurement and Modification Paradigms. Alcohol Clin Exp Res. 2015; 39(10):2047-55. PMC: 5054858. DOI: 10.1111/acer.12853. View

Garavan H, Pankiewicz J, Bloom A, Cho J, Sperry L, Ross T . Cue-induced cocaine craving: neuroanatomical specificity for drug users and drug stimuli. Am J Psychiatry. 2000; 157(11):1789-98. DOI: 10.1176/appi.ajp.157.11.1789. View

10.

Stritzke W, Breiner M, Curtin J, Lang A . Assessment of substance cue reactivity: advances in reliability, specificity, and validity. Psychol Addict Behav. 2004; 18(2):148-59. DOI: 10.1037/0893-164X.18.2.148. View

11.

Borsboom D, Mellenbergh G, van Heerden J . The concept of validity. Psychol Rev. 2004; 111(4):1061-71. DOI: 10.1037/0033-295X.111.4.1061. View

12.

Grusser S, Wrase J, Klein S, Hermann D, Smolka M, Ruf M . Cue-induced activation of the striatum and medial prefrontal cortex is associated with subsequent relapse in abstinent alcoholics. Psychopharmacology (Berl). 2004; 175(3):296-302. DOI: 10.1007/s00213-004-1828-4. View

13.

Wrase J, Schlagenhauf F, Kienast T, Wustenberg T, Bermpohl F, Kahnt T . Dysfunction of reward processing correlates with alcohol craving in detoxified alcoholics. Neuroimage. 2007; 35(2):787-94. DOI: 10.1016/j.neuroimage.2006.11.043. View

14.

Billieux J, Khazaal Y, Oliveira S, de Timary P, Edel Y, Zebouni F . The Geneva Appetitive Alcohol Pictures (GAAP): development and preliminary validation. Eur Addict Res. 2011; 17(5):225-30. DOI: 10.1159/000328046. View

15.

Buckman J, White H, Bates M . Psychophysiological reactivity to emotional picture cues two years after college students were mandated for alcohol interventions. Addict Behav. 2010; 35(8):786-90. PMC: 2872043. DOI: 10.1016/j.addbeh.2010.03.017. View

16.

Heinz A, Wrase J, Kahnt T, Beck A, Bromand Z, Grusser S . Brain activation elicited by affectively positive stimuli is associated with a lower risk of relapse in detoxified alcoholic subjects. Alcohol Clin Exp Res. 2007; 31(7):1138-47. DOI: 10.1111/j.1530-0277.2007.00406.x. View

17.

Grusser S, Heinz A, Flor H . Standardized stimuli to assess drug craving and drug memory in addicts. J Neural Transm (Vienna). 2000; 107(6):715-20. DOI: 10.1007/s007020070072. View

18.

Lukas S, Lowen S, Lindsey K, Conn N, Tartarini W, Rodolico J . Extended-release naltrexone (XR-NTX) attenuates brain responses to alcohol cues in alcohol-dependent volunteers: a bold FMRI study. Neuroimage. 2013; 78:176-85. DOI: 10.1016/j.neuroimage.2013.03.055. View

19.

Fey W, Moggi F, Rohde K, Michel C, Seitz A, Stein M . Development of stimulus material for research in alcohol use disorders. Int J Methods Psychiatr Res. 2016; 26(1). PMC: 6877281. DOI: 10.1002/mpr.1527. View

20.

Olofsson J, Polich J . Affective visual event-related potentials: arousal, repetition, and time-on-task. Biol Psychol. 2007; 75(1):101-8. PMC: 1885422. DOI: 10.1016/j.biopsycho.2006.12.006. View