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The Pathogenesis of Resection-Associated Intestinal Adaptation

Overview
Specialty Gastroenterology
Date 2016 Oct 11
PMID 27722191
Citations 30
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Abstract

After massive small-bowel resection, the remnant bowel compensates by a process termed . Adaptation is characterized by villus elongation and crypt deepening, which increases the capacity for absorption and digestion per unit length. The mechanisms/mediators of this important response are multiple. The purpose of this review is to highlight the major basic contributions in elucidating a more comprehensive understanding of this process.

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