Advances in Nanomaterials and Their Applications in Point of Care (POC) Devices for the Diagnosis of Infectious Diseases

Overview

Journal Biotechnol Adv

Specialties Biochemistry
Biotechnology

Date 2016 Oct 1

PMID 27686397

Citations 16

Authors

Dai Thien Nhan Tram

Hao Wang

Sigit Sugiarto

Tao Li

Wee Han Ang

Chengkuo Lee

Giorgia Pastorin

Affiliations

Soon will be listed here.

Abstract

Nanotechnology has gained much attention over the last decades, as it offers unique opportunities for the advancement of the next generation of sensing tools. Point-of-care (POC) devices for the selective detection of biomolecules using engineered nanoparticles have become a main research thrust in the diagnostic field. This review presents an overview on how the POC-associated nanotechnology, currently applied for the identification of nucleic acids, proteins and antibodies, might be further exploited for the detection of infectious pathogens: although still premature, future integrations of nanoparticles with biological markers that target specific microorganisms will enable timely therapeutic intervention against life-threatening infectious diseases.

Citing Articles

Fluorescence Polarization Assay for Infection Diagnostics: A Review.

Eremin S, Mukhametova L, Krylov V, Nifantiev N Molecules. 2024; 29(19).

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Emerging Trends of Gold Nanostructures for Point-of-Care Biosensor-Based Detection of COVID-19.

Yadav A, Basavegowda N, Shirin S, Raju S, Sekar R, Somu P Mol Biotechnol. 2024; .

PMID: 38703305 DOI: 10.1007/s12033-024-01157-y.

A Mechanical Assay for the Quantification of Anti-RBD IgG Levels in Finger-Prick Whole Blood.

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Development of gold nanoparticles-lateral flow test as a novel field diagnostic assay for detecting foot-and-mouth disease and lumpy skin disease viruses.

Abdalhamed A, Naser S, Mohamed A, Zeedan G Iran J Microbiol. 2023; 14(4):574-586.

PMID: 36721504 PMC: 9867639. DOI: 10.18502/ijm.v14i4.10245.

Emerging 0D, 1D, 2D, and 3D nanostructures for efficient point-of-care biosensing.

Byakodi M, Shrikrishna N, Sharma R, Bhansali S, Mishra Y, Kaushik A Biosens Bioelectron X. 2022; 12:100284.

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References

Li W, Zhao D . Extension of the Stöber method to construct mesoporous SiO2 and TiO2 shells for uniform multifunctional core-shell structures. Adv Mater. 2013; 25(1):142-9. DOI: 10.1002/adma.201203547. View

Tang D, Tang J, Su B, Ren J, Chen G . Simultaneous determination of five-type hepatitis virus antigens in 5 min using an integrated automatic electrochemical immunosensor array. Biosens Bioelectron. 2009; 25(7):1658-62. DOI: 10.1016/j.bios.2009.12.004. View

Wakai J, Takagi A, Nakayama M, Miya T, Miyahara T, Iwanaga T . A novel method of identifying genetic mutations using an electrochemical DNA array. Nucleic Acids Res. 2004; 32(18):e141. PMC: 524315. DOI: 10.1093/nar/gnh141. View

Tarantola D, OMalley J, Mann J . The HIV/AIDS pandemic and the global response. Hygie. 1993; 12(2):5-11, 45-6. View

Takahashi S, Metcalf C, Ferrari M, Moss W, Truelove S, Tatem A . Reduced vaccination and the risk of measles and other childhood infections post-Ebola. Science. 2015; 347(6227):1240-2. PMC: 4691345. DOI: 10.1126/science.aaa3438. View

Chen L, Zhang X, Zhou G, Xiang X, Ji X, Zheng Z . Simultaneous determination of human Enterovirus 71 and Coxsackievirus B3 by dual-color quantum dots and homogeneous immunoassay. Anal Chem. 2012; 84(7):3200-7. DOI: 10.1021/ac203172x. View

Rouet F, Rouzioux C . HIV-1 viral load testing cost in developing countries: what's new?. Expert Rev Mol Diagn. 2007; 7(6):703-7. DOI: 10.1586/14737159.7.6.703. View

Baeumner A, Cohen R, Miksic V, Min J . RNA biosensor for the rapid detection of viable Escherichia coli in drinking water. Biosens Bioelectron. 2003; 18(4):405-13. DOI: 10.1016/s0956-5663(02)00162-8. View

Ye Y, Zhao J, Yan F, Zhu Y, Ju H . Electrochemical behavior and detection of hepatitis B virus DNA PCR production at gold electrode. Biosens Bioelectron. 2003; 18(12):1501-8. DOI: 10.1016/s0956-5663(03)00121-0. View

10.

Phillips R, Miranda O, You C, Rotello V, Bunz U . Rapid and efficient identification of bacteria using gold-nanoparticle-poly(para-phenyleneethynylene) constructs. Angew Chem Int Ed Engl. 2008; 47(14):2590-4. DOI: 10.1002/anie.200703369. View

11.

Yeung S, Lee T, Cai H, Hsing I . A DNA biochip for on-the-spot multiplexed pathogen identification. Nucleic Acids Res. 2006; 34(18):e118. PMC: 1636451. DOI: 10.1093/nar/gkl702. View

12.

Liu S, Ju H . Reagentless glucose biosensor based on direct electron transfer of glucose oxidase immobilized on colloidal gold modified carbon paste electrode. Biosens Bioelectron. 2003; 19(3):177-83. DOI: 10.1016/s0956-5663(03)00172-6. View

13.

Lu X, Tuan H, Korgel B, Xia Y . Facile synthesis of gold nanoparticles with narrow size distribution by using AuCl or AuBr as the precursor. Chemistry. 2007; 14(5):1584-91. PMC: 2492888. DOI: 10.1002/chem.200701570. View

14.

Moayeri M, Wiggins J, Leppla S . Anthrax protective antigen cleavage and clearance from the blood of mice and rats. Infect Immun. 2007; 75(11):5175-84. PMC: 2168306. DOI: 10.1128/IAI.00719-07. View

15.

Tokel O, Inci F, Demirci U . Advances in plasmonic technologies for point of care applications. Chem Rev. 2014; 114(11):5728-52. PMC: 4086846. DOI: 10.1021/cr4000623. View

16.

Cai H, Xu Y, Zhu N, He P, Fang Y . An electrochemical DNA hybridization detection assay based on a silver nanoparticle label. Analyst. 2002; 127(6):803-8. DOI: 10.1039/b200555g. View

17.

Niemeyer C, Ceyhan B . DNA-Directed Functionalization of Colloidal Gold with Proteins This work was supported by Deutsche Forschungsgemeinschaft and Fonds der Chemischen Industrie. We thank Prof. D. Blohm for helpful discussions and generous support. . Angew Chem Int Ed Engl. 2001; 40(19):3685-3688. DOI: 10.1002/1521-3773(20011001)40:19<3685::aid-anie3685>3.0.co;2-e. View

18.

Cui H, Xu T, Sun Y, Zhou A, Cui Y, Liu W . Hairpin DNA as a biobarcode modified on gold nanoparticles for electrochemical DNA detection. Anal Chem. 2014; 87(2):1358-65. DOI: 10.1021/ac504206n. View

19.

Galow T, Rodrigo J, Cleary K, Cooke G, Rotello V . Fluorocarbonylferrocene. A Versatile Intermediate for Ferrocene Esters and Amides. J Org Chem. 2001; 64(10):3745-3746. DOI: 10.1021/jo982219q. View

20.

Wang J, Li J, Baca A, Hu J, Zhou F, Yan W . Amplified voltammetric detection of DNA hybridization via oxidation of ferrocene caps on gold nanoparticle/streptavidin conjugates. Anal Chem. 2003; 75(15):3941-5. DOI: 10.1021/ac0344079. View