Centrosome Movement in the Early Divisions of Caenorhabditis Elegans: a Cortical Site Determining Centrosome Position

Overview

Journal J Cell Biol

Specialty Cell Biology

Date 1989 Sep 1

PMID 2768338

Citations 68

Authors

A A Hyman

Affiliations

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Abstract

In Caenorhabditis elegans embryos, early blastomeres of the P cell lineage divide successively on the same axis. This axis is a consequence of the specific rotational movement of the pair of centrosomes and nucleus (Hyman, A. A., and J. G. White. 1987. J. Cell Biol. 105:2123-2135). A laser has been used to perturb the centrosome movements that determine the pattern of early embryonic divisions. The results support a previously proposed model in which a centrosome rotates towards its correct position by shortening of connections, possibly microtubules, between a centrosome and a defined site on the cortex of the embryo.

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