Layer-by-Layer Encapsulation of Probiotics for Delivery to the Microbiome

Overview

Journal Adv Mater

Date 2016 Sep 13

PMID 27616140

Citations 80

Authors

Aaron C Anselmo

Kevin J McHugh

Jamie Webster

Robert Langer

Ana Jaklenec

Affiliations

Soon will be listed here.

Abstract

The gastrointestinal (GI) microbiome is widely investigated for its role in many diseases. However, technologies designed for microbiome delivery are lacking. Here, a layer-by-layer (LbL) approach is reported for probiotic encapsulation to protect probiotics against GI tract insults and improve their adhesion and growth on the intestines. These advantages translate to significantly enhanced survival of LbL-probiotics in vivo.

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