Tissue Engineering in Burn Scar Reconstruction

Overview

Journal Burns Trauma

Publisher Oxford University Press

Date 2016 Aug 31

PMID 27574664

Citations 6

Authors

Ppm van Zuijlen

Klm Gardien

Meh Jaspers

E J Bos

D C Baas

Ajm van Trier

E Middelkoop

Affiliations

Soon will be listed here.

Abstract

Nowadays, most patients with severe burns will survive their injury. This evolution is accompanied by the challenge to cover a large percentage of total body surface area burned. Consequently, more and more patients have to deal with the sequelae of burn scars and require (multiple) reconstructions. This review provides a gross overview of developments in the field of tissue engineering for permanent burn wound coverage and reconstructive burn surgery, focusing on usage and clinical effectiveness. Not only skin substitutes will be discussed but also the replacement of subcutaneous fat tissue and cartilage.

Citing Articles

Engineering 3D-Printed Bioresorbable Scaffold to Improve Non-Vascularized Fat Grafting: A Proof-of-Concept Study.

Jordao A, Cleret D, Dhayer M, Le Rest M, Cao S, Rech A Biomedicines. 2023; 11(12).

PMID: 38137558 PMC: 10741522. DOI: 10.3390/biomedicines11123337.

Clinical applications of acellular dermal matrices: A review.

Petrie K, Cox C, Becker B, Mackay B Scars Burn Heal. 2022; 8:20595131211038313.

PMID: 35083065 PMC: 8785275. DOI: 10.1177/20595131211038313.

Burn injury.

Jeschke M, van Baar M, Choudhry M, Chung K, Gibran N, Logsetty S Nat Rev Dis Primers. 2020; 6(1):11.

PMID: 32054846 PMC: 7224101. DOI: 10.1038/s41572-020-0145-5.

Endothelial cells enhance adipose mesenchymal stromal cell-mediated matrix contraction via ALK receptors and reduced follistatin: Potential role of endothelial cells in skin fibrosis.

Monsuur H, van den Broek L, Koolwijk P, Niessen F, Gibbs S J Cell Physiol. 2018; 233(10):6714-6722.

PMID: 29345319 PMC: 6056025. DOI: 10.1002/jcp.26494.

Hypertrophic scarring: the greatest unmet challenge after burn injury.

Finnerty C, Jeschke M, Branski L, Barret J, Dziewulski P, Herndon D Lancet. 2016; 388(10052):1427-1436.

PMID: 27707499 PMC: 5380137. DOI: 10.1016/S0140-6736(16)31406-4.

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