Symptomatic Peripheral Artery Disease is Associated with Decreased Long-term Survival After Coronary Artery Bypass: a Contemporary Retrospective Analysis

Overview

Journal Surg Today

Specialty General Surgery

Date 2016 Jul 23

PMID 27444027

Citations 2

Authors

Teruya Nakamura

Koichi Toda

Shigeru Miyagawa

Yasushi Yoshikawa

Satsuki Fukushima

Shunsuke Saito

Daisuke Yoshioka

Shin Yajima

Shohei Yoshida

Yoshiki Sawa

Affiliations

Soon will be listed here.

Abstract

Purpose: Little has been documented about whether the severity of peripheral artery disease (PAD) affects the postoperative outcomes of coronary artery bypass grafting (CABG).

Methods: We performed a retrospective analysis of 683 patients who underwent isolated CABG, comparing preoperative profiles and postoperative outcomes between patients with PAD (n = 116) and those without PAD (n = 567). Kaplan-Meier analysis was done to examine the long-term survival and the Cox proportional hazard model was used to establish the preoperative risk factors associated with survival.

Results: The PAD patients were older and had more preoperative comorbidities than those without PAD. There were three operative deaths in each group (p = 0.07). The patients with PAD had more postoperative complications related to transfusion requirement (p = 0.004), the need for re-exploration for bleeding (p = 0.04), longer ventilation time (p < 0.001), and longer ICU stay (p = 0.001), than those without PAD. The 10-year survival rate of the PAD patients was lower than that of the non-PAD patients (p < 0.001). Univariate and multivariate analyses revealed that symptomatic PAD (p = 0.008) was associated with decreased long-term survival.

Conclusion: Symptomatic PAD was found to be an independent factor for poor long-term survival after CABG. Thus, aggressive screening measures for coronary disease, early surgical revascularization, and secondary prevention may improve the early and long-term outcomes of these patients.

Citing Articles

Non-coronary atherosclerosis: a marker of poor prognosis in patients undergoing coronary artery bypass surgery.

Gonzalez-Lorenzo O, Franco Pelaez J, Kallmeyer A, Nieto L, Esteban L, Pello A Front Cardiovasc Med. 2024; 11:1305162.

PMID: 38464841 PMC: 10921089. DOI: 10.3389/fcvm.2024.1305162.

Impact of established cardiovascular disease on 10-year death after coronary revascularization for complex coronary artery disease.

Wang R, Garg S, Gao C, Kawashima H, Ono M, Hara H Clin Res Cardiol. 2021; 110(10):1680-1691.

PMID: 34432113 PMC: 8484091. DOI: 10.1007/s00392-021-01922-y.

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