Heterocycle Formation Palladium-Catalyzed C-H Functionalization

Overview

Journal Synthesis (Stuttg)

Publisher Thieme

Specialty Chemistry

Date 2016 Jul 12

PMID 27397938

Citations 14

Authors

Tian-Sheng Mei

Lei Kou

Sandy Ma

Keary M Engle

Jin-Quan Yu

Affiliations

Soon will be listed here.

Abstract

Heterocyclic compounds are ubiquitous in natural products, pharmaceuticals, and agrochemicals. Therefore, the design of novel protocols to construct heterocycles more efficiently is a major area of focus in the organic chemistry. In the past several years, cyclization reactions based upon palladium-catalyzed C-H activation have received substantial attention due to their capacity for expediting heterocycle synthesis. This review discusses strategies for heterocycle synthesis palladium-catalyzed C-H bond activation and highlights recent examples from the literature.

Citing Articles

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A novel Pd-catalysed sequential carbonylation/cyclization approach toward bis--heterocycles: rationalization by electronic structure calculations.

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