A Novel Species of Torque Teno Mini Virus (TTMV) in Gingival Tissue from Chronic Periodontitis Patients

Overview

Journal Sci Rep

Specialty Science

Date 2016 May 26

PMID 27221159

Citations 18

Authors

Yu Zhang

Fei Li

Tong-Ling Shan

Xutao Deng

Eric Delwart

Xi-Ping Feng

Affiliations

Soon will be listed here.

Abstract

A new species of torque teno mini virus, named TTMV-222, was detected in gingival tissue from periodontitis patients using a viral metagenomics method. The 2803-nucleotide genome of TTMV-222 is closely related to TTMV1-CBD279, with 62.6% overall nucleotide similarity. Genetic analyses of the new virus genome revealed a classic genomic organization but a weak identity with known sequences. The prevalence of TTMV-222 in the periodontitis group (n = 150) was significantly higher than that in the healthy group (n = 150) (p = 0.032), suggesting that the new virus may be associated with inflammation in chronic periodontitis patients. However, this finding requires further investigation.

Citing Articles

Novel Virus Identification through Metagenomics: A Systematic Review.

Bassi C, Guerriero P, Pierantoni M, Callegari E, Sabbioni S Life (Basel). 2022; 12(12).

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Metagenomic Analysis Reveals High Abundance of Torque Teno Mini Virus in the Respiratory Tract of Children with Acute Respiratory Illness.

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and periodontitis: a case-control study and identification of five novel redondoviruses from periodontal tissues.

Zhang Y, Wang C, Feng X, Chen X, Zhang W Virus Evol. 2022; 7(1):veab033.

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Viruses of the oral cavity: Prevalence, pathobiology and association with oral diseases.

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Taxonomic update for mammalian anelloviruses (family Anelloviridae).

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