Citrate-Based Biomaterials and Their Applications in Regenerative Engineering

Overview

Journal Annu Rev Mater Res

Publisher Annual Reviews

Specialty Biomedical Engineering

Date 2016 Mar 23

PMID 27004046

Citations 46

Authors

Richard T Tran

Jian Yang

Guillermo A Ameer

Affiliations

Soon will be listed here.

Abstract

Advances in biomaterials science and engineering are crucial to translating regenerative engineering, an emerging field that aims to recreate complex tissues, into clinical practice. In this regard, citrate-based biomaterials have become an important tool owing to their versatile material and biological characteristics including unique antioxidant, antimicrobial, adhesive, and fluorescent properties. This review discusses fundamental design considerations, strategies to incorporate unique functionality, and examples of how citrate-based biomaterials can be an enabling technology for regenerative engineering.

Citing Articles

Highly Elastic, Biodegradable Polyester-Based Citrate Rubber for 3D Printing in Regenerative Engineering.

Khan A, Ding Y, Fu R, Wang X, Mendez-Santos M, Adepu S ACS Biomater Sci Eng. 2025; 11(3):1571-1582.

PMID: 39928332 PMC: 11897938. DOI: 10.1021/acsbiomaterials.4c01486.

In situ formation of micro/nano phase composite for 3D printing clinically relevant bioresorbable stents.

Ware H, Ding Y, Collins C, Akar B, Akbari N, Wang H Mater Today Chem. 2025; 26.

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Advances and challenges in regenerative therapies for abdominal aortic aneurysm.

Chao C, Applewhite B, Reddy N, Matiuto N, Dang C, Jiang B Front Cardiovasc Med. 2024; 11:1369785.

PMID: 38895536 PMC: 11183335. DOI: 10.3389/fcvm.2024.1369785.

Phase-changing citrate macromolecule combats oxidative pancreatic islet damage, enables islet engraftment and function in the omentum.

Burke J, Zhu Y, Zhang X, Rios P, Joshi I, Lopez D Sci Adv. 2024; 10(23):eadk3081.

PMID: 38848367 PMC: 11160476. DOI: 10.1126/sciadv.adk3081.

Citric Acid: A Nexus Between Cellular Mechanisms and Biomaterial Innovations.

Xu H, Yan S, Gerhard E, Xie D, Liu X, Zhang B Adv Mater. 2024; 36(32):e2402871.

PMID: 38801111 PMC: 11309907. DOI: 10.1002/adma.202402871.

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