Caffeine and Cardiovascular Diseases: Critical Review of Current Research

Overview

Journal Eur J Nutr

Specialty Nutritional Sciences

Date 2016 Mar 3

PMID 26932503

Citations 29

Authors

Anthony Zulli

Renee M Smith

Peter Kubatka

Jan Novak

Yoshio Uehara

Hayley Loftus

Tawar Qaradakhi

Miroslav Pohanka

Nazarii Kobyliak

Angela Zagatina

Jan Klimas

Alan Hayes

Giampiero La Rocca

Miroslav Soucek

Peter Kruzliak

Affiliations

Soon will be listed here.

Abstract

Caffeine is a most widely consumed physiological stimulant worldwide, which is consumed via natural sources, such as coffee and tea, and now marketed sources such as energy drinks and other dietary supplements. This wide use has led to concerns regarding the safety of caffeine and its proposed beneficial role in alertness, performance and energy expenditure and side effects in the cardiovascular system. The question remains "Which dose is safe?", as the population does not appear to adhere to the strict guidelines listed on caffeine consumption. Studies in humans and animal models yield controversial results, which can be explained by population, type and dose of caffeine and low statistical power. This review will focus on comprehensive and critical review of the current literature and provide an avenue for further study.

Citing Articles

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Coffee intake leads to preeclampsia-like syndromes in susceptible pregnant rats.

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The risk of premature cardiac contractions (PAC/PVC) related to caffeine consumption among healthcare workers: A comprehensive review.

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Is Coffee and Tea a Threat or Ally to Cardiovascular Health?.

Mendpara V, Garg S, Shah P, Bhavsar J, Anamika F, Patel M Cureus. 2024; 15(12):e49991.

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Orange/far-red hybrid voltage indicators with reduced phototoxicity enable reliable long-term imaging in neurons and cardiomyocytes.

Liu S, Ling J, Chen P, Cao C, Peng L, Zhang Y Proc Natl Acad Sci U S A. 2023; 120(34):e2306950120.

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