A Contact-lens-on-a-chip Companion Diagnostic Tool for Personalized Medicine

Overview

Journal Lab Chip

Publisher Royal Society of Chemistry

Specialties Biotechnology
Chemistry

Date 2016 Mar 1

PMID 26923038

Citations 6

Authors

Allan Guan

Yi Wang

K Scott Phillips

Zhenyu Li

Affiliations

Soon will be listed here.

Abstract

We present a novel, microfluidic platform that integrates human tears (1 μL) with commercial contact lens materials to provide personalized assessment of lens care solution performance. This device enabled the detection of significant differences in cleaning and disinfection outcomes between subjects and between biofilms vs. planktonic bacteria.

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A Method for Developing Novel 3D Cornea-on-a-Chip Using Primary Murine Corneal Epithelial and Endothelial Cells.

Bai J, Fu H, Bazinet L, Birsner A, DAmato R Front Pharmacol. 2020; 11:453.

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Organoids and Microphysiological Systems: New Tools for Ophthalmic Drug Discovery.

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