Effective Disinfectants for and
Overview
Affiliations
The lack of published data on effective disinfectants and contact times for use on the fungal pathogens and prompted the authors to investigate the fungicidal activity of three commonly used laboratory disinfectants on arthroconidia harvested from strain 2009. They tested the ability of 10% bleach, 70% ethanol, and Vesphene IIse to inactivate 10 arthroconidia in an aqueous suspension within 1, 2, 5, 10, or 20 minutes of contact time. Both 10% bleach and 70% ethanol provided a 7-log reduction in arthroconidia in less than 1 minute, with no growth observed at any of the tested time points. Vesphene IIse was less effective, providing a 6-log reduction in arthroconidia after 5 minutes, but was unable to completely inactivate all of the arthroconidia, even after 20 minutes of contact time.
Mead H, Caballero Van Dyke M, Barker B Curr Protoc Microbiol. 2020; 58(1):e113.
PMID: 32894648 PMC: 9976608. DOI: 10.1002/cpmc.113.
Mitchell N, Magee D, Grys T, Lake D Appl Biosaf. 2019; 24(1):30-33.
PMID: 30962770 PMC: 6449853. DOI: 10.1177/1535676018818560.
Characterizing in vitro spherule morphogenesis of multiple strains of both species of Coccidioides.
Mead H, Teixeira M, Galgiani J, Barker B Med Mycol. 2018; 57(4):478-488.
PMID: 30053114 PMC: 6506604. DOI: 10.1093/mmy/myy049.