Vitrified/warmed Single Blastocyst Transfer in Preimplantation Genetic Diagnosis/preimplantation Genetic Screening Cycles

Overview

Journal Int J Clin Exp Med

Specialty General Medicine

Date 2016 Feb 18

PMID 26885112

Citations 3

Authors

Jin Huang

Rong Li

Ying Lian

Lixue Chen

Xiaodan Shi

Jie Qiao

Ping Liu

Affiliations

Soon will be listed here.

Abstract

Objective: To investigate the single blastocyst transfer in preimplantation genetic diagnosis (PGD)/preimplantation genetic screening (PGS) cycles.

Methods: 80 PGD/PGS cycles undergoing blastocyst biopsy were studied. There were 88 warming cycles during the study period. Only one warmed blastocyst was transferred per cycle. The outcomes were followed up to the infants were born.

Results: The embryo implantation rate was 54.55% (48/88). The clinical pregnancy rate was 54.55% (48/88) per transfer cycle and 60% (48/80) per initial PGD/PGS cycle. There was no multi-pregnant in this study. The live birth rate was 42.05% (37/88) per transfer cycle and 46.25% (37/80) per initial PGD/PGS cycle.

Conclusion: In PGD/PGS cycles, single blastocyst transfer reduces the multiple pregnancy rate without affecting the clinical outcomes.

Citing Articles

Variations in chromosomal aneuploidy rates in IVF blastocysts and early spontaneous abortion chorionic villi.

Zhang X, Wang Y, Zhao N, Liu P, Huang J J Assist Reprod Genet. 2020; 37(3):527-537.

PMID: 31903515 PMC: 7125276. DOI: 10.1007/s10815-019-01682-9.

Overall Blastocyst Quality, Trophectoderm Grade, and Inner Cell Mass Grade Predict Pregnancy Outcome in Euploid Blastocyst Transfer Cycles.

Zhao Y, Yu Y, Zhang X Chin Med J (Engl). 2018; 131(11):1261-1267.

PMID: 29786036 PMC: 5987494. DOI: 10.4103/0366-6999.232808.

Comparative study of single-nucleotide polymorphism array and next generation sequencing based strategies on triploid identification in preimplantation genetic diagnosis and screen.

Xu J, Niu W, Peng Z, Bao X, Zhang M, Wang L Oncotarget. 2016; 7(49):81839-81848.

PMID: 27833086 PMC: 5348434. DOI: 10.18632/oncotarget.13247.

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