» Articles » PMID: 26872510

Potential of APDM Mobility Lab for the Monitoring of the Progression of Parkinson's Disease

Overview
Specialties Pharmacology
Radiology
Date 2016 Feb 14
PMID 26872510
Citations 66
Authors
Affiliations
Soon will be listed here.
Abstract

APDM's Mobility Lab system provides portable, validated, reliable, objective measures of balance and gait that are sensitive to Parkinson's disease (PD). In this review, we describe the potential of objective measures collected with the Mobility Lab system for tracking longitudinal progression of PD. Balance and gait are among the most important motor impairments influencing quality of life for people with PD. Mobility Lab uses body-worn, Opal sensors on the legs, trunk and arms during prescribed tasks, such as the instrumented Get Up and Go test or quiet stance, to quickly quantify the quality of balance and gait in the clinical environment. The same Opal sensors can be sent home with patients to continuously monitor the quality of their daily activities. Objective measures have the potential to monitor progression of mobility impairments in PD throughout its course to improve patient care and accelerate clinical trials.

Citing Articles

Commercial symptom monitoring devices in Parkinson's disease: benefits, limitations, and trends.

Rodriguez-Martin D, Perez-Lopez C Front Neurol. 2025; 15:1470928.

PMID: 39764292 PMC: 11700807. DOI: 10.3389/fneur.2024.1470928.


Concurrent Validity and Relative Reliability of the RunScribe™ System for the Assessment of Spatiotemporal Gait Parameters During Walking.

Rafales-Perucha A, Bravo-Vinuales E, Molina-Molina A, Carton-Llorente A, Cardiel-Sanchez S, Roche-Seruendo L Sensors (Basel). 2024; 24(23).

PMID: 39686362 PMC: 11644950. DOI: 10.3390/s24237825.


The Effects of a Floss Band on Ankle Range of Motion, Balance, and Gait in Chronic Stroke: A Randomized Controlled Study.

Moon B, Kim J Healthcare (Basel). 2024; 12(23).

PMID: 39685006 PMC: 11640843. DOI: 10.3390/healthcare12232384.


Predicting future fallers in Parkinson's disease using kinematic data over a period of 5 years.

Sotirakis C, Brzezicki M, Patel S, Conway N, FitzGerald J, Antoniades C NPJ Digit Med. 2024; 7(1):345.

PMID: 39638907 PMC: 11621420. DOI: 10.1038/s41746-024-01311-5.


Assessing Changes in Motor Function and Mobility in Individuals with Parkinson's Disease After 12 Sessions of Patient-Specific Adaptive Dynamic Cycling.

Kim Y, Smith B, Shigo L, Shaikh A, Loparo K, Ridgel A Sensors (Basel). 2024; 24(22).

PMID: 39599140 PMC: 11598193. DOI: 10.3390/s24227364.


References
1.
Collomb-Clerc A, Welter M . Effects of deep brain stimulation on balance and gait in patients with Parkinson's disease: A systematic neurophysiological review. Neurophysiol Clin. 2015; 45(4-5):371-88. DOI: 10.1016/j.neucli.2015.07.001. View

2.
Sterling N, Cusumano J, Shaham N, Piazza S, Liu G, Kong L . Dopaminergic modulation of arm swing during gait among Parkinson's disease patients. J Parkinsons Dis. 2014; 5(1):141-50. PMC: 4609542. DOI: 10.3233/JPD-140447. View

3.
Lopane G, Mellone S, Chiari L, Cortelli P, Calandra-Buonaura G, Contin M . Dyskinesia detection and monitoring by a single sensor in patients with Parkinson's disease. Mov Disord. 2015; 30(9):1267-71. DOI: 10.1002/mds.26313. View

4.
Stocchi F, Ruggieri S, Brughitta G, Agnoli A . Problems in daily motor performances in Parkinson's disease: the continuous dopaminergic stimulation. J Neural Transm Suppl. 1986; 22:209-18. View

5.
Spain R, Mancini M, Horak F, Bourdette D . Body-worn sensors capture variability, but not decline, of gait and balance measures in multiple sclerosis over 18 months. Gait Posture. 2014; 39(3):958-64. PMC: 4010096. DOI: 10.1016/j.gaitpost.2013.12.010. View