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Mitochondrial Damage Induces Senescence with a Twisted Arm

Overview
Journal Cell Metab
Publisher Cell Press
Date 2016 Feb 11
PMID 26863485
Citations 5
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Abstract

Cellular senescence is a damage response characterized by a stable cell-cycle arrest and an intense secretion of cytokines. In this issue of Cell Metabolism, Wiley et al. (2016) report that, in the case of mitochondrial damage, senescence occurs with an atypical secretory phenotype, in both adipose tissue and skin.

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