Vascular Restoration Therapy and Bioresorbable Vascular Scaffold

Overview

Journal Regen Biomater

Specialty Biomedical Engineering

Date 2016 Jan 28

PMID 26816624

Citations 13

Authors

Yunbing Wang

Xingdong Zhang

Affiliations

Soon will be listed here.

Abstract

This article describes the evolution of minimally invasive intervention technologies for vascular restoration therapy from early-stage balloon angioplasty in 1970s, metallic bare metal stent and metallic drug-eluting stent technologies in 1990s and 2000s, to bioresorbable vascular scaffold (BVS) technology in large-scale development in recent years. The history, the current stage, the challenges and the future of BVS development are discussed in detail as the best available approach for vascular restoration therapy. The criteria of materials selection, design and processing principles of BVS, and the corresponding clinical trial results are also summarized in this article.

Citing Articles

Development of 4D-Printed Arterial Stents Utilizing Bioinspired Architected Auxetic Materials.

Kladovasilakis N, Kyriakidis I, Tzimtzimis E, Pechlivani E, Tsongas K, Tzetzis D Biomimetics (Basel). 2025; 10(2).

PMID: 39997102 PMC: 11852449. DOI: 10.3390/biomimetics10020078.

A comprehensive study on venous endovascular management and stenting in deep veins occlusion and stenosis: A review study.

Salimi J, Chinisaz F, Yazdi S Surg Open Sci. 2024; 19:131-140.

PMID: 38690401 PMC: 11058076. DOI: 10.1016/j.sopen.2024.04.001.

A drug-free cardiovascular stent functionalized with tailored collagen supports in-situ healing of vascular tissues.

Wu H, Yang L, Luo R, Li L, Zheng T, Huang K Nat Commun. 2024; 15(1):735.

PMID: 38272886 PMC: 10810808. DOI: 10.1038/s41467-024-44902-2.

Advances in Fabrication Technologies for the Development of Next-Generation Cardiovascular Stents.

Das A, Mehrotra S, Kumar A J Funct Biomater. 2023; 14(11).

PMID: 37998113 PMC: 10672426. DOI: 10.3390/jfb14110544.

An extracellular matrix-mimetic coating with dual bionics for cardiovascular stents.

Chen N, Li M, Wu H, Qin Y, Wang J, Xu K Regen Biomater. 2023; 10:rbad055.

PMID: 37359731 PMC: 10287914. DOI: 10.1093/rb/rbad055.

References

Oberhauser J, Hossainy S, Rapoza R . Design principles and performance of bioresorbable polymeric vascular scaffolds. EuroIntervention. 2011; 5 Suppl F:F15-22. DOI: 10.4244/EIJV5IFA3. View

Serruys P, Kutryk M, Ong A . Coronary-artery stents. N Engl J Med. 2006; 354(5):483-95. DOI: 10.1056/NEJMra051091. View

Bainey K, Norris C, Graham M, Ghali W, Knudtson M, Welsh R . Clinical in-stent restenosis with bare metal stents: is it truly a benign phenomenon?. Int J Cardiol. 2007; 128(3):378-82. DOI: 10.1016/j.ijcard.2007.06.024. View

Nishio S, Kosuga K, Igaki K, Okada M, Kyo E, Tsuji T . Long-Term (>10 Years) clinical outcomes of first-in-human biodegradable poly-l-lactic acid coronary stents: Igaki-Tamai stents. Circulation. 2012; 125(19):2343-53. DOI: 10.1161/CIRCULATIONAHA.110.000901. View

Purnama A, Hermawan H, Champetier S, Mantovani D, Couet J . Gene expression profile of mouse fibroblasts exposed to a biodegradable iron alloy for stents. Acta Biomater. 2013; 9(10):8746-53. DOI: 10.1016/j.actbio.2013.02.033. View

Khattab A, Windecker S . Vascular restoration therapy: what should the clinical and angiographic measures for success be?. EuroIntervention. 2011; 5 Suppl F:F49-53. DOI: 10.4244/EIJV5IFA8. View

Rao S, Califf R, Kramer J, Peterson E, Gross T, Pepine C . Postmarket evaluation of breakthrough technologies. Am Heart J. 2008; 156(2):201-8. DOI: 10.1016/j.ahj.2008.01.036. View

Davlouros P, Nikokiris G, Karantalis V, Mavronasiou E, Xanthopoulou I, Damelou A . Neointimal coverage and stent strut apposition six months after implantation of a paclitaxel eluting stent in acute coronary syndromes: an optical coherence tomography study. Int J Cardiol. 2010; 151(2):155-9. DOI: 10.1016/j.ijcard.2010.05.004. View

Onuma Y, Serruys P . Bioresorbable scaffold: the advent of a new era in percutaneous coronary and peripheral revascularization?. Circulation. 2011; 123(7):779-97. DOI: 10.1161/CIRCULATIONAHA.110.971606. View

10.

Schatz R, Baim D, Leon M, ELLIS S, Goldberg S, Hirshfeld J . Clinical experience with the Palmaz-Schatz coronary stent. Initial results of a multicenter study. Circulation. 1991; 83(1):148-61. DOI: 10.1161/01.cir.83.1.148. View

11.

Gogas B, Farooq V, Onuma Y, Serruys P . The ABSORB bioresorbable vascular scaffold: an evolution or revolution in interventional cardiology?. Hellenic J Cardiol. 2012; 53(4):301-9. View

12.

Ormiston J, Serruys P . Bioabsorbable coronary stents. Circ Cardiovasc Interv. 2009; 2(3):255-60. DOI: 10.1161/CIRCINTERVENTIONS.109.859173. View

13.

Kahn J, Hartzler G . Frequency and causes of failure with contemporary balloon coronary angioplasty and implications for new technologies. Am J Cardiol. 1990; 66(10):858-60. DOI: 10.1016/0002-9149(90)90366-9. View

14.

Bourke S, Kohn J . Polymers derived from the amino acid L-tyrosine: polycarbonates, polyarylates and copolymers with poly(ethylene glycol). Adv Drug Deliv Rev. 2003; 55(4):447-66. DOI: 10.1016/s0169-409x(03)00038-3. View

15.

Martin D, Boyle F . Drug-eluting stents for coronary artery disease: a review. Med Eng Phys. 2010; 33(2):148-63. DOI: 10.1016/j.medengphy.2010.10.009. View

16.

Tamai H, Igaki K, Kyo E, Kosuga K, Kawashima A, Matsui S . Initial and 6-month results of biodegradable poly-l-lactic acid coronary stents in humans. Circulation. 2000; 102(4):399-404. DOI: 10.1161/01.cir.102.4.399. View

17.

Gao R, Xu B, Lansky A, Yang Y, Ma C, Han Y . A randomised comparison of a novel abluminal groove-filled biodegradable polymer sirolimus-eluting stent with a durable polymer everolimus-eluting stent: clinical and angiographic follow-up of the TARGET I trial. EuroIntervention. 2013; 9(1):75-83. DOI: 10.4244/EIJV9I1A12. View

18.

Brugaletta S, Garcia-Garcia H, Onuma Y, Serruys P . Everolimus-eluting ABSORB bioresorbable vascular scaffold: present and future perspectives. Expert Rev Med Devices. 2012; 9(4):327-38. DOI: 10.1586/erd.12.17. View

19.

Serruys P, Ormiston J, Onuma Y, Regar E, Gonzalo N, Garcia-Garcia H . A bioabsorbable everolimus-eluting coronary stent system (ABSORB): 2-year outcomes and results from multiple imaging methods. Lancet. 2009; 373(9667):897-910. DOI: 10.1016/S0140-6736(09)60325-1. View

20.

Gruntzig A, SENNING A, SIEGENTHALER W . Nonoperative dilatation of coronary-artery stenosis: percutaneous transluminal coronary angioplasty. N Engl J Med. 1979; 301(2):61-8. DOI: 10.1056/NEJM197907123010201. View