Quality of Life: A Critical Outcome for All Surgical Treatments of Gastric Cancer

Overview

Journal World J Gastroenterol

Publisher Baishideng Publishing Group

Specialty Gastroenterology

Date 2016 Jan 27

PMID 26811650

Citations 34

Authors

Michael D McCall

Peter J Graham

Oliver F Bathe

Affiliations

Soon will be listed here.

Abstract

Surgery represents the main curative therapeutic modality for gastric cancer, and it is occasionally considered for palliation as well as prophylaxis. Most frequently, surgical outcomes are conveyed in terms of oncological outcomes such as recurrence and survival. However, quality of life (QoL) is also important and should be considered when making treatment decisions - including the extent of and approach to surgery. Measurement of QoL usually involves the application of questionnaires. While there are multiple QoL questionnaires validated for use in oncology patients, there are very few that have been validated for use in those with gastric cancer. In this review, we discuss and compare the current status of QoL questionnaires in gastric cancer. More importantly, the impact of surgery for treatment, palliation and prophylaxis of gastric cancer on QoL will be described. These data should inform the surgeon on the optimal approach to treating gastric cancer, taking into account oncological outcomes. Knowledge gaps are also identified, providing a roadmap for future studies.

Citing Articles

Function Preserving Gastrectomy and Quality of Life.

Kim J, Lee H J Gastric Cancer. 2025; 25(1):247-260.

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Morbidity and quality of life of totally laparoscopic versus laparoscopy-assisted distal gastrectomy for early gastric cancer: a multi-center prospective randomized controlled trial (CKLASS01).

Zhang Y, Li Z, Tian Y, Yu J, Wang J, Lee C Gastric Cancer. 2024; 28(1):131-144.

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JingRu C, GuoHui M, Lili G, ZhenYu C, MingHua Z, ZeLong Y Surg Endosc. 2024; 38(8):4215-4221.

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References

Nakamura M, Kido Y, Yano M, Hosoya Y . Reliability and validity of a new scale to assess postoperative dysfunction after resection of upper gastrointestinal carcinoma. Surg Today. 2005; 35(7):535-42. DOI: 10.1007/s00595-005-2988-5. View

Troidl H, Kusche J, Vestweber K, Eypasch E, Maul U . Pouch versus esophagojejunostomy after total gastrectomy: a randomized clinical trial. World J Surg. 1987; 11(6):699-712. DOI: 10.1007/BF01656592. View

Nakamura M, Kido Y, Hosoya Y, Yano M, Nagai H, Monden M . Postoperative gastrointestinal dysfunction after 2-field versus 3-field lymph node dissection in patients with esophageal cancer. Surg Today. 2007; 37(5):379-82. DOI: 10.1007/s00595-006-3413-4. View

Nakamura M, Kido Y, Egawa T . Development of a 32-item scale to assess postoperative dysfunction after upper gastrointestinal cancer resection. J Clin Nurs. 2008; 17(11):1440-9. DOI: 10.1111/j.1365-2702.2007.02179.x. View

Cunningham S, Schulick R . Palliative management of gastric cancer. Surg Oncol. 2007; 16(4):267-75. DOI: 10.1016/j.suronc.2007.08.004. View

Hayashi H, Ochiai T, Shimada H, Gunji Y . Prospective randomized study of open versus laparoscopy-assisted distal gastrectomy with extraperigastric lymph node dissection for early gastric cancer. Surg Endosc. 2005; 19(9):1172-6. DOI: 10.1007/s00464-004-8207-4. View

Kim A, Cho J, Hsu Y, Choi M, Noh J, Sohn T . Changes of quality of life in gastric cancer patients after curative resection: a longitudinal cohort study in Korea. Ann Surg. 2012; 256(6):1008-13. DOI: 10.1097/SLA.0b013e31827661c9. View

Nakada K, Ikeda M, Takahashi M, Kinami S, Yoshida M, Uenosono Y . Characteristics and clinical relevance of postgastrectomy syndrome assessment scale (PGSAS)-45: newly developed integrated questionnaires for assessment of living status and quality of life in postgastrectomy patients. Gastric Cancer. 2014; 18(1):147-58. DOI: 10.1007/s10120-014-0344-4. View

Wu C, Hsiung C, Lo S, Hsieh M, Chen J, Li A . Nodal dissection for patients with gastric cancer: a randomised controlled trial. Lancet Oncol. 2006; 7(4):309-15. DOI: 10.1016/S1470-2045(06)70623-4. View

10.

de Bree E, Charalampakis V, Melissas J, Tsiftsis D . The extent of lymph node dissection for gastric cancer: a critical appraisal. J Surg Oncol. 2010; 102(6):552-62. DOI: 10.1002/jso.21646. View

11.

Park S, Chung H, Lee S, Kwon O, Yu W . Serial comparisons of quality of life after distal subtotal or total gastrectomy: what are the rational approaches for quality of life management?. J Gastric Cancer. 2014; 14(1):32-8. PMC: 3996247. DOI: 10.5230/jgc.2014.14.1.32. View

12.

Samarasam I, Chandran B, Sitaram V, Perakath B, Nair A, Mathew G . Palliative gastrectomy in advanced gastric cancer: is it worthwhile?. ANZ J Surg. 2006; 76(1-2):60-3. DOI: 10.1111/j.1445-2197.2006.03649.x. View

13.

Conroy T, Marchal F, Blazeby J . Quality of life in patients with oesophageal and gastric cancer: an overview. Oncology. 2007; 70(6):391-402. DOI: 10.1159/000099034. View

14.

Vinuela E, Gonen M, Brennan M, Coit D, Strong V . Laparoscopic versus open distal gastrectomy for gastric cancer: a meta-analysis of randomized controlled trials and high-quality nonrandomized studies. Ann Surg. 2012; 255(3):446-56. DOI: 10.1097/SLA.0b013e31824682f4. View

15.

Kaptein A, Morita S, Sakamoto J . Quality of life in gastric cancer. World J Gastroenterol. 2005; 11(21):3189-96. PMC: 4316047. DOI: 10.3748/wjg.v11.i21.3189. View

16.

Kaminishi M, Yamaguchi H, Shimizu N, Nomura S, Yoshikawa A, Hashimoto M . Stomach-partitioning gastrojejunostomy for unresectable gastric carcinoma. Arch Surg. 1997; 132(2):184-7. DOI: 10.1001/archsurg.1997.01430260082018. View

17.

Garland S, Pelletier G, Lawe A, Biagioni B, Easaw J, Eliasziw M . Prospective evaluation of the reliability, validity, and minimally important difference of the functional assessment of cancer therapy-gastric (FACT-Ga) quality-of-life instrument. Cancer. 2010; 117(6):1302-12. DOI: 10.1002/cncr.25556. View

18.

Lin S, Tong H, You T, Yu Y, Wu W, Chen C . Palliative gastrectomy and chemotherapy for stage IV gastric cancer. J Cancer Res Clin Oncol. 2007; 134(2):187-92. DOI: 10.1007/s00432-007-0268-z. View

19.

Blair V, Martin I, Shaw D, Winship I, Kerr D, Arnold J . Hereditary diffuse gastric cancer: diagnosis and management. Clin Gastroenterol Hepatol. 2006; 4(3):262-75. DOI: 10.1016/j.cgh.2005.12.003. View

20.

Cunningham S, Kamangar F, Kim M, Hammoud S, Haque R, Maitra A . Survival after gastric adenocarcinoma resection: eighteen-year experience at a single institution. J Gastrointest Surg. 2005; 9(5):718-25. DOI: 10.1016/j.gassur.2004.12.002. View