Effect of Carbodiimide on the Fatigue Crack Growth Resistance of Resin-dentin Bonds

Overview

Journal Dent Mater

Specialty Dentistry

Date 2016 Jan 8

PMID 26739775

Citations 8

Authors

Zihou Zhang

Dylan Beitzel

Hessam Majd

Mustafa Mutluay

Arzu Tezvergil-Mutluay

Franklin R Tay

David H Pashley

Dwayne Arola

Affiliations

Soon will be listed here.

Abstract

Unlabelled: Recent studies have shown that ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC) inactivates endogenous dentin proteases, thereby preventing collagen degradation and improving the durability of adhesive bonds to dentin. Bond durability is routinely assessed by monotonic microtensile testing, which does not consider the cyclic nature of mastication.

Objective: To characterize the effect of an EDC pretreatment on the fatigue crack growth behavior of resin-dentin bonds.

Methods: Bonded interface Compact Tension (CT) specimens were prepared using a three-step etch-and-rinse adhesive and hybrid resin-composite. Adhesive bonding of the treated groups included a 1 min application of an experimental EDC conditioner to the acid-etched dentin. The control groups did not receive EDC treatment. The fatigue crack growth resistance was examined after storage in artificial saliva for 0, 3 and 6 months.

Results: There was no significant difference in the immediate fatigue crack growth resistance of the EDC-treated and control groups at 0 months. However, after the 3 and 6 months storage periods the EDC-treated groups exhibited significantly greater (p≤0.05) fatigue crack growth resistance than the control specimens.

Significance: Although the EDC treatment maintained the fatigue crack growth resistance of the dentin bonds through 6 months of storage, additional studies are needed to assess its effectiveness over longer periods and in relation to other cross-linking agents.

Citing Articles

Effect of applying carbodiimide combined with a two-step self-etch adhesive durability.

Tang L, Zhang Y, Liu Y, Chen X, Li Y, Zhu L BMC Oral Health. 2024; 24(1):667.

PMID: 38849778 PMC: 11162073. DOI: 10.1186/s12903-024-04415-2.

Effect of collagen cross-linkers on dentin bond strength: A systematic review and network meta-analysis.

Chen H, Sun G, Wang H, Yu S, Tian Z, Zhu S Front Bioeng Biotechnol. 2023; 10:1100894.

PMID: 36760752 PMC: 9903368. DOI: 10.3389/fbioe.2022.1100894.

Effect of Collagen Crosslinkers on Dentin Bond Strength of Adhesive Systems: A Systematic Review and Meta-Analysis.

Hardan L, Daood U, Bourgi R, Cuevas-Suarez C, Devoto W, Zarow M Cells. 2022; 11(15).

PMID: 35954261 PMC: 9368291. DOI: 10.3390/cells11152417.

Influence of two carbodiimides on the bond strength of universal adhesives to dentin.

Fernandes A, Silva R, Muller M, da Cunha L, Correr G, Gonzaga C Odontology. 2021; 110(1):99-105.

PMID: 34279762 DOI: 10.1007/s10266-021-00642-z.

Fatigue resistance of dentin bonds prepared with two- vs. three-step adhesives: Effect of carbodiimide.

Zhang Z, Beitzel D, Majd H, Mutluay M, Tezvergil-Mutluay A, Tay F Dent Mater. 2017; 33(12):1340-1350.

PMID: 28942948 PMC: 5709219. DOI: 10.1016/j.dental.2017.08.192.

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