Arterial Compliance Measurement in Overweight and Hypertensive Children

Overview

Journal Indian J Pediatr

Specialty Pediatrics

Date 2015 Dec 16

PMID 26666902

Citations 8

Authors

Mirjam Mocnik

Sara Nikolic

Natasa Marcun Varda

Affiliations

Soon will be listed here.

Abstract

Objectives: To investigate the pulse wave velocity (PWV) and augmentation index (Alx), measures of arterial stiffness, in relation to hypertension and obesity, the main risk factors for cardiovascular diseases.

Methods: Two groups of pediatric patients, 31 children and adolescents with hypertension and 85 with overweight, were analysed and compared to the control group (50 healthy individuals). Subjects were sampled by opportunity sampling at the Department of Pediatrics, Maribor. In each patient, blood pressure, anthropometrical parameters and PWV measurements using the applanation tonometry technique were performed.

Results: There was a significant correlation between PWV and age (r = 0.461, p = 0.001) in the control group, whereas no correlation was obtained between PWV and body mass index (BMI) or central mean arterial pressure (CMAP). In the hypertensive group, PWV only correlated with CMAP (r = 0.496, p = 0.005). A significant correlation was found in the overweight group between PWV and both age and BMI (r = 0.484, p < 0.001 and r = 0.347, p = 0.001, respectively). Alx results were not taken into consideration.

Conclusions: The results of this pilot study show that overweight and hypertensive children and adolescents are associated with less compliant arteries than their healthy peers, which could be used for screening of patients with expected early cardiovascular risk.

Citing Articles

Unveiling the Silent Danger of Childhood Obesity: Non-Invasive Biomarkers Such as Carotid Intima-Media Thickness, Arterial Stiffness Surrogate Markers, and Blood Pressure Are Useful in Detecting Early Vascular Alterations in Obese Children.

Mihuta M, Paul C, Borlea A, Roi C, Velea-Barta O, Mozos I Biomedicines. 2023; 11(7).

PMID: 37509481 PMC: 10376407. DOI: 10.3390/biomedicines11071841.

Evaluating the Arterial Stiffness as a Useful Tool in the Management of Obese Children.

Mihuta M, Stoian D, Borlea A, Roi C, Velea-Barta O, Mozos I Children (Basel). 2023; 10(2).

PMID: 36832311 PMC: 9955158. DOI: 10.3390/children10020183.

The Oscillometric Pulse Wave Analysis Is Useful in Evaluating the Arterial Stiffness of Obese Children with Relevant Cardiometabolic Risks.

Mihuta M, Paul C, Borlea A, Cepeha C, Velea I, Mozos I J Clin Med. 2022; 11(17).

PMID: 36079009 PMC: 9457050. DOI: 10.3390/jcm11175078.

Cardiovascular Risk Factors in Children with Obesity, Preventive Diagnostics and Possible Interventions.

Mocnik M, Marcun Varda N Metabolites. 2021; 11(8).

PMID: 34436493 PMC: 8398426. DOI: 10.3390/metabo11080551.

Childhood Obesity: Does it Have Any Effect on Young Arteries?.

Jakab A, Hidvegi E, Illyes M, Cziraki A, Kalmar T, Maroti Z Front Pediatr. 2020; 8:389.

PMID: 32766188 PMC: 7378393. DOI: 10.3389/fped.2020.00389.

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