The Glioma International Case-Control Study: A Report From the Genetic Epidemiology of Glioma International Consortium

Overview

Journal Am J Epidemiol

Publisher Oxford University Press

Specialty Public Health

Date 2015 Dec 15

PMID 26656478

Citations 38

Authors

E Susan Amirian

Georgina N Armstrong

Renke Zhou

Ching C Lau

Elizabeth B Claus

Jill S Barnholtz-Sloan

Dora Ilyasova

Joellen Schildkraut

Francis Ali-Osman

Siegal Sadetzki

Christoffer Johansen

Richard S Houlston

Robert B Jenkins

Daniel Lachance

Sara H Olson

Jonine L Bernstein

Ryan T Merrell

Margaret R Wrensch

Faith G Davis

Rose Lai

Sanjay Shete

Christopher I Amos

Michael E Scheurer

Kenneth Aldape

Irina Alafuzoff

Thomas Brannstrom

Helle Broholm

Peter Collins

Caterina Giannini

Marc Rosenblum

Tarik Tihan

Beatrice S Melin

Melissa L Bondy

Affiliations

Soon will be listed here.

Abstract

Decades of research have established only a few etiological factors for glioma, which is a rare and highly fatal brain cancer. Common methodological challenges among glioma studies include small sample sizes, heterogeneity of tumor subtypes, and retrospective exposure assessment. Here, we briefly describe the Glioma International Case-Control (GICC) Study (recruitment, 2010-2013), a study being conducted by the Genetic Epidemiology of Glioma International Consortium that integrates data from multiple data collection sites, uses a common protocol and questionnaire, and includes biospecimen collection. To our knowledge, the GICC Study is the largest glioma study to date that includes collection of blood samples, which will allow for genetic analysis and interrogation of gene-environment interactions.

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