WormBase 2016: Expanding to Enable Helminth Genomic Research

Overview

Journal Nucleic Acids Res

Publisher Oxford University Press

Specialty Biochemistry

Date 2015 Nov 19

PMID 26578572

Citations 204

Authors

Kevin L Howe

Bruce J Bolt

Scott Cain

Juancarlos Chan

Wen J Chen

Paul Davis

James Done

Thomas Down

Sibyl Gao

Christian Grove

Todd W Harris

Ranjana Kishore

Raymond Lee

Jane Lomax

Yuling Li

Hans-Michael Muller

Cecilia Nakamura

Paulo Nuin

Michael Paulini

Daniela Raciti

Gary Schindelman

Eleanor Stanley

Mary Ann Tuli

Kimberly Van Auken

Daniel Wang

Xiaodong Wang

Gary Williams

Adam Wright

Karen Yook

Matthew Berriman

Paul Kersey

Tim Schedl

Lincoln Stein

Paul W Sternberg

Affiliations

Soon will be listed here.

Abstract

WormBase (www.wormbase.org) is a central repository for research data on the biology, genetics and genomics of Caenorhabditis elegans and other nematodes. The project has evolved from its original remit to collect and integrate all data for a single species, and now extends to numerous nematodes, ranging from evolutionary comparators of C. elegans to parasitic species that threaten plant, animal and human health. Research activity using C. elegans as a model system is as vibrant as ever, and we have created new tools for community curation in response to the ever-increasing volume and complexity of data. To better allow users to navigate their way through these data, we have made a number of improvements to our main website, including new tools for browsing genomic features and ontology annotations. Finally, we have developed a new portal for parasitic worm genomes. WormBase ParaSite (parasite.wormbase.org) contains all publicly available nematode and platyhelminth annotated genome sequences, and is designed specifically to support helminth genomic research.

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