Long-Term Monitoring of Physical Behavior Reveals Different Cardiac Responses to Physical Activity Among Subjects with and Without Chronic Neck Pain

Overview

Journal Biomed Res Int

Publisher Wiley

Specialties Biomedical Engineering
Biotechnology
General Medicine

Date 2015 Nov 12

PMID 26557711

Citations 3

Authors

David M Hallman

Svend Erik Mathiassen

Eugene Lyskov

Affiliations

Soon will be listed here.

Abstract

Background: We determined the extent to which heart rate variability (HRV) responses to daily physical activity differ between subjects with and without chronic neck pain.

Method: Twenty-nine subjects (13 women) with chronic neck pain and 27 age- and gender-matched healthy controls participated. Physical activity (accelerometry), HRV (heart rate monitor), and spatial location (Global Positioning System (GPS)) were recorded for 74 hours. GPS data were combined with a diary to identify periods of work and of leisure at home and elsewhere. Time- and frequency-domain HRV indices were calculated and stratified by period and activity type (lying/sitting, standing, or walking). ANCOVAs with multiple adjustments were used to disclose possible group differences in HRV.

Results: The pain group showed a reduced HRV response to physical activity compared with controls (p = .001), according to the sympathetic-baroreceptor HRV index (LF/HF, ratio between low- and high-frequency power), even after adjustment for leisure time physical activity, work stress, sleep quality, mental health, and aerobic capacity (p = .02). The parasympathetic response to physical activity did not differ between groups.

Conclusions: Relying on long-term monitoring of physical behavior and heart rate variability, we found an aberrant sympathetic-baroreceptor response to daily physical activity among subjects with chronic neck pain.

Citing Articles

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References

. Heart rate variability. Standards of measurement, physiological interpretation, and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Eur Heart J. 1996; 17(3):354-81. View

Chalaye P, Lafrenaye S, Goffaux P, Marchand S . The role of cardiovascular activity in fibromyalgia and conditioned pain modulation. Pain. 2013; 155(6):1064-1069. DOI: 10.1016/j.pain.2013.12.023. View

Melanson E . Resting heart rate variability in men varying in habitual physical activity. Med Sci Sports Exerc. 2000; 32(11):1894-901. DOI: 10.1097/00005768-200011000-00012. View

Keadle S, Lyden K, Amanda Hickey , Ray E, Fowke J, Freedson P . Validation of a previous day recall for measuring the location and purpose of active and sedentary behaviors compared to direct observation. Int J Behav Nutr Phys Act. 2014; 11:12. PMC: 3922158. DOI: 10.1186/1479-5868-11-12. View

Celis-Morales C, Perez-Bravo F, Ibanez L, Salas C, Bailey M, Gill J . Objective vs. self-reported physical activity and sedentary time: effects of measurement method on relationships with risk biomarkers. PLoS One. 2012; 7(5):e36345. PMC: 3348936. DOI: 10.1371/journal.pone.0036345. View

Li J, Loerbroks A, Angerer P . Physical activity and risk of cardiovascular disease: what does the new epidemiological evidence show?. Curr Opin Cardiol. 2013; 28(5):575-83. DOI: 10.1097/HCO.0b013e328364289c. View

Li J, Siegrist J . Physical activity and risk of cardiovascular disease--a meta-analysis of prospective cohort studies. Int J Environ Res Public Health. 2012; 9(2):391-407. PMC: 3315253. DOI: 10.3390/ijerph9020391. View

Goldstein D, Bentho O, Park M, Sharabi Y . Low-frequency power of heart rate variability is not a measure of cardiac sympathetic tone but may be a measure of modulation of cardiac autonomic outflows by baroreflexes. Exp Physiol. 2011; 96(12):1255-61. PMC: 3224799. DOI: 10.1113/expphysiol.2010.056259. View

Thayer J, Yamamoto S, Brosschot J . The relationship of autonomic imbalance, heart rate variability and cardiovascular disease risk factors. Int J Cardiol. 2009; 141(2):122-31. DOI: 10.1016/j.ijcard.2009.09.543. View

10.

Ware Jr J, Gandek B . Overview of the SF-36 Health Survey and the International Quality of Life Assessment (IQOLA) Project. J Clin Epidemiol. 1998; 51(11):903-12. DOI: 10.1016/s0895-4356(98)00081-x. View

11.

Pinna G, Maestri R, Torunski A, Danilowicz-Szymanowicz L, Szwoch M, La Rovere M . Heart rate variability measures: a fresh look at reliability. Clin Sci (Lond). 2007; 113(3):131-40. DOI: 10.1042/CS20070055. View

12.

White D, Raven P . Autonomic neural control of heart rate during dynamic exercise: revisited. J Physiol. 2014; 592(12):2491-500. PMC: 4080933. DOI: 10.1113/jphysiol.2014.271858. View

13.

Lannersten L, Kosek E . Dysfunction of endogenous pain inhibition during exercise with painful muscles in patients with shoulder myalgia and fibromyalgia. Pain. 2010; 151(1):77-86. DOI: 10.1016/j.pain.2010.06.021. View

14.

Harrington D, Welk G, Donnelly A . Validation of MET estimates and step measurement using the ActivPAL physical activity logger. J Sports Sci. 2011; 29(6):627-33. DOI: 10.1080/02640414.2010.549499. View

15.

Berntson G, BIGGER Jr J, Eckberg D, Grossman P, Kaufmann P, Malik M . Heart rate variability: origins, methods, and interpretive caveats. Psychophysiology. 1997; 34(6):623-48. DOI: 10.1111/j.1469-8986.1997.tb02140.x. View

16.

Olsen R, Bruehl S, Nielsen C, Rosseland L, Eggen A, Stubhaug A . Hypertension prevalence and diminished blood pressure-related hypoalgesia in individuals reporting chronic pain in a general population: the Tromsø study. Pain. 2012; 154(2):257-262. DOI: 10.1016/j.pain.2012.10.020. View

17.

Rimoldi O, Furlan R, Pagani M, Piazza S, Guazzi M, Pagani M . Analysis of neural mechanisms accompanying different intensities of dynamic exercise. Chest. 1992; 101(5 Suppl):226S-230S. DOI: 10.1378/chest.101.5_supplement.226s. View

18.

Andersen L, Blangsted A, Nielsen P, Hansen L, Vedsted P, Sjogaard G . Effect of cycling on oxygenation of relaxed neck/shoulder muscles in women with and without chronic pain. Eur J Appl Physiol. 2010; 110(2):389-94. DOI: 10.1007/s00421-010-1517-4. View

19.

Gockel M, Lindholm H, Alaranta H, Viljanen A, Lindquist A, Lindholm T . Cardiovascular functional disorder and stress among patients having neck-shoulder symptoms. Ann Rheum Dis. 1995; 54(6):494-7. PMC: 1009909. DOI: 10.1136/ard.54.6.494. View

20.

Apkarian A, Bushnell M, Treede R, Zubieta J . Human brain mechanisms of pain perception and regulation in health and disease. Eur J Pain. 2005; 9(4):463-84. DOI: 10.1016/j.ejpain.2004.11.001. View