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Photoreceptor Disc Morphogenesis: The Classical Evagination Model Prevails

Overview
Journal J Cell Biol
Specialty Cell Biology
Date 2015 Nov 4
PMID 26527745
Citations 4
Authors
Edward N Pugh Jr
Affiliations
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Abstract

Vision begins in photoreceptor outer segments with light captured by opsins in continually synthesized disc membranes. The process by which rod photoreceptor discs are formed has been controversial. In this issue, Ding et al. (2015. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201508093) show conclusively that rod discs are formed by plasma membrane evagination.

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