Chemical Libraries: How Dark is HTS Dark Matter?

Overview

Journal Nat Chem Biol

Specialties Biochemistry
Biology
Chemistry

Date 2015 Oct 20

PMID 26479440

Citations 4

Authors

Ricardo Macarron

Affiliations

Soon will be listed here.

Citing Articles

"Molecular Anatomy": a new multi-dimensional hierarchical scaffold analysis tool.

Manelfi C, Gemei M, Talarico C, Cerchia C, Fava A, Lunghini F J Cheminform. 2021; 13:54.

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Creating and screening natural product libraries.

Wilson B, Thornburg C, Henrich C, Grkovic T, OKeefe B Nat Prod Rep. 2020; 37(7):893-918.

PMID: 32186299 PMC: 8494140. DOI: 10.1039/c9np00068b.

Predicted Biological Activity of Purchasable Chemical Space.

Irwin J, Gaskins G, Sterling T, Mysinger M, Keiser M J Chem Inf Model. 2017; 58(1):148-164.

PMID: 29193970 PMC: 5780839. DOI: 10.1021/acs.jcim.7b00316.

Molecular Connectivity Predefines Polypharmacology: Aliphatic Rings, Chirality, and sp Centers Enhance Target Selectivity.

Monteleone S, Fuchs J, Liedl K Front Pharmacol. 2017; 8:552.

PMID: 28894419 PMC: 5581349. DOI: 10.3389/fphar.2017.00552.

References

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