Diagnosis of Food Allergy

Overview

Journal Pediatr Clin North Am

Specialty Pediatrics

Date 2015 Oct 13

PMID 26456439

Citations 13

Authors

Rebecca Sharon Chinthrajah

Dana Tupa

Benjamin T Prince

Whitney Morgan Block

Jaime Sou Rosa

Anne Marie Singh

Kari Nadeau

Affiliations

Soon will be listed here.

Abstract

The prevalence of food allergies has been on the increase over the last 2 decades. Diagnosing food allergies can be complicated, as there are multiple types that have distinct clinical and immunologic features. Food allergies are broadly classified into immunoglobulin E (IgE)-mediated, non-IgE-mediated, or mixed food allergic reactions. This review focuses on the clinical manifestations of the different categories of food allergies and the different tests available to guide the clinician toward an accurate diagnosis.

Citing Articles

Food Allergies and Parasites in Children.

Packi K, Rudek A, Matysiak J, Klimczak S, Matuszewska E, Rzetecka N Foods. 2023; 12(13).

PMID: 37444203 PMC: 10340500. DOI: 10.3390/foods12132465.

Pathogenesis of allergic diseases and implications for therapeutic interventions.

Wang J, Zhou Y, Zhang H, Hu L, Liu J, Wang L Signal Transduct Target Ther. 2023; 8(1):138.

PMID: 36964157 PMC: 10039055. DOI: 10.1038/s41392-023-01344-4.

T-cell epitope discovery and single-cell technologies to advance food allergy research.

Lewis S, Peters B J Allergy Clin Immunol. 2022; 151(1):15-20.

PMID: 36411114 PMC: 9825656. DOI: 10.1016/j.jaci.2022.10.025.

Case Reports of Cow's Milk Protein Allergy Presenting as Delayed Passage of Meconium With Early Onset Infant Constipation.

Madala A, Lure A, Cheng S, Cheng S Front Pediatr. 2022; 10:858476.

PMID: 35498816 PMC: 9051367. DOI: 10.3389/fped.2022.858476.

Clinical Manifestations of Pediatric Food Allergy: a Contemporary Review.

Wang L, Mu S, Lin M, Sung T, Chiang B, Lin C Clin Rev Allergy Immunol. 2021; 62(1):180-199.

PMID: 34519995 DOI: 10.1007/s12016-021-08895-w.

References

Katz Y, Goldberg M . Natural history of food protein-induced enterocolitis syndrome. Curr Opin Allergy Clin Immunol. 2014; 14(3):229-39. PMC: 4011630. DOI: 10.1097/ACI.0000000000000053. View

Monti G, Castagno E, Liguori S, Lupica M, Tarasco V, Viola S . Food protein-induced enterocolitis syndrome by cow's milk proteins passed through breast milk. J Allergy Clin Immunol. 2010; 127(3):679-80. DOI: 10.1016/j.jaci.2010.10.017. View

Finkel Y, Sandstedt B, Karpe B . Proctocolitis in exclusively breast-fed infants. Eur J Pediatr. 1996; 155(6):464-7. DOI: 10.1007/BF01955182. View

Zapatero Remon L, Alonso Lebrero E, Martin Fernandez E, Martinez Molero M . Food-protein-induced enterocolitis syndrome caused by fish. Allergol Immunopathol (Madr). 2005; 33(6):312-6. DOI: 10.1016/s0301-0546(05)73249-3. View

Arvola T, Ruuska T, Keranen J, Hyoty H, Salminen S, Isolauri E . Rectal bleeding in infancy: clinical, allergological, and microbiological examination. Pediatrics. 2006; 117(4):e760-8. DOI: 10.1542/peds.2005-1069. View

Caubet J, Kondo Y, Urisu A, Nowak-Wegrzyn A . Molecular diagnosis of egg allergy. Curr Opin Allergy Clin Immunol. 2011; 11(3):210-5. DOI: 10.1097/ACI.0b013e3283464d1b. View

Rothenberg M . Eosinophilic gastrointestinal disorders (EGID). J Allergy Clin Immunol. 2004; 113(1):11-28. DOI: 10.1016/j.jaci.2003.10.047. View

Gonzalez-Cervera J, Angueira T, Rodriguez-Dominguez B, Arias A, Yague-Compadre J, Lucendo A . Successful food elimination therapy in adult eosinophilic esophagitis: not all patients are the same. J Clin Gastroenterol. 2012; 46(10):855-8. DOI: 10.1097/MCG.0b013e3182432259. View

Fabbro S, Zirwas M . Systemic contact dermatitis to foods: nickel, BOP, and more. Curr Allergy Asthma Rep. 2014; 14(10):463. DOI: 10.1007/s11882-014-0463-3. View

10.

Arora A, Yamazaki K . Eosinophilic esophagitis: asthma of the esophagus?. Clin Gastroenterol Hepatol. 2004; 2(7):523-30. DOI: 10.1016/s1542-3565(04)00236-8. View

11.

Assaad A . Eosinophilic gastrointestinal disorders. Allergy Asthma Proc. 2009; 30(1):17-22. DOI: 10.2500/aap.2009.30.3189. View

12.

Hwang J, Kang K, Kang Y, Kim A . Probiotic gastrointestinal allergic reaction caused by Saccharomyces boulardii. Ann Allergy Asthma Immunol. 2009; 103(1):87-8. DOI: 10.1016/S1081-1206(10)60154-8. View

13.

Lake A . Food-induced eosinophilic proctocolitis. J Pediatr Gastroenterol Nutr. 2000; 30 Suppl:S58-60. DOI: 10.1097/00005176-200001001-00009. View

14.

Du Toit G, Roberts G, Sayre P, Plaut M, Bahnson H, Mitchell H . Identifying infants at high risk of peanut allergy: the Learning Early About Peanut Allergy (LEAP) screening study. J Allergy Clin Immunol. 2012; 131(1):135-43.e1-12. DOI: 10.1016/j.jaci.2012.09.015. View

15.

Commins S, Satinover S, Hosen J, Mozena J, Borish L, Lewis B . Delayed anaphylaxis, angioedema, or urticaria after consumption of red meat in patients with IgE antibodies specific for galactose-alpha-1,3-galactose. J Allergy Clin Immunol. 2008; 123(2):426-33. PMC: 3324851. DOI: 10.1016/j.jaci.2008.10.052. View

16.

Hansen K, Ballmer-Weber B, Sastre J, Lidholm J, Andersson K, Oberhofer H . Component-resolved in vitro diagnosis of hazelnut allergy in Europe. J Allergy Clin Immunol. 2009; 123(5):1134-41, 1141.e1-3. DOI: 10.1016/j.jaci.2009.02.005. View

17.

Moissidis I, Chaidaroon D, Vichyanond P, Bahna S . Milk-induced pulmonary disease in infants (Heiner syndrome). Pediatr Allergy Immunol. 2005; 16(6):545-52. DOI: 10.1111/j.1399-3038.2005.00291.x. View

18.

Lake A, Whitington P, Hamilton S . Dietary protein-induced colitis in breast-fed infants. J Pediatr. 1982; 101(6):906-10. DOI: 10.1016/s0022-3476(82)80008-5. View

19.

Mehr S, Kakakios A, Frith K, Kemp A . Food protein-induced enterocolitis syndrome: 16-year experience. Pediatrics. 2009; 123(3):e459-64. DOI: 10.1542/peds.2008-2029. View

20.

Heaps A, Carter S, Selwood C, Moody M, Unsworth J, Deacock S . The utility of the ISAC allergen array in the investigation of idiopathic anaphylaxis. Clin Exp Immunol. 2014; 177(2):483-90. PMC: 4226599. DOI: 10.1111/cei.12334. View