Bariatric Surgery in Type 1 Diabetes Mellitus: A Systematic Review

Overview

Journal Obes Surg

Date 2015 Oct 11

PMID 26452482

Citations 8

Authors

Kamal K Mahawar

Nimantha De Alwis

William R J Carr

Neil Jennings

Norbert Schroeder

Peter K Small

Affiliations

Soon will be listed here.

Abstract

Bariatric surgery is recognised as an effective treatment strategy for obese patients with type 2 diabetes mellitus. An increasing number of patients with type 1 diabetes mellitus also suffer with obesity and obesity-associated comorbidities but the role of bariatric and metabolic surgery in this group of patients is unclear. This systematic review investigates published English language scientific literature to understand the results of bariatric surgery in obese patients with type 1 diabetes mellitus. We found that these patients can experience significant weight loss and comorbidity resolution with bariatric surgery. Though most patients also see a decline in total insulin requirement, glycaemic control remains difficult. Most of the patients reported in literature have undergone gastric bypass but data is insufficient to recommend any particular procedure.

Citing Articles

Obesity in Patients with Type 1 Diabetes: Links, Risks and Management Challenges.

Vilarrasa N, San Jose P, Rubio M, Lecube A Diabetes Metab Syndr Obes. 2021; 14:2807-2827.

PMID: 34188505 PMC: 8232956. DOI: 10.2147/DMSO.S223618.

Management of Diabetes in Patients Undergoing Bariatric Surgery.

Mulla C, Baloch H, Hafida S Curr Diab Rep. 2019; 19(11):112.

PMID: 31686263 DOI: 10.1007/s11892-019-1242-2.

Reversibility of diabetes mellitus: Narrative review of the evidence.

Ang G World J Diabetes. 2018; 9(7):127-131.

PMID: 30079148 PMC: 6068740. DOI: 10.4239/wjd.v9.i7.127.

Biopsychosocial Aspects of Weight Management in Type 1 Diabetes: a Review and Next Steps.

Driscoll K, Corbin K, Maahs D, Pratley R, Bishop F, Kahkoska A Curr Diab Rep. 2017; 17(8):58.

PMID: 28660565 PMC: 6053070. DOI: 10.1007/s11892-017-0892-1.

Long-Term Outcomes in Patients with Morbid Obesity and Type 1 Diabetes Undergoing Bariatric Surgery.

Vilarrasa N, Rubio M, Minambres I, Flores L, Caixas A, Ciudin A Obes Surg. 2016; 27(4):856-863.

PMID: 27709487 DOI: 10.1007/s11695-016-2390-y.

References

Cossu M, Noya G, Tonolo G, Profili S, Meloni G, Ruggiu M . Duodenal switch without gastric resection: results and observations after 6 years. Obes Surg. 2004; 14(10):1354-9. DOI: 10.1381/0960892042583851. View

Ngiam K, Lee W, Lee Y, Cheng A . Efficacy of metabolic surgery on HbA1c decrease in type 2 diabetes mellitus patients with BMI <35 kg/m2--a review. Obes Surg. 2013; 24(1):148-58. DOI: 10.1007/s11695-013-1112-y. View

Chillaron J, Flores Le-Roux J, Benaiges D, Pedro-Botet J . Type 1 diabetes, metabolic syndrome and cardiovascular risk. Metabolism. 2013; 63(2):181-7. DOI: 10.1016/j.metabol.2013.10.002. View

Reyes Garcia R, Romero Munoz M, Galbis Verdu H . Bariatric surgery in type 1 diabetes. Endocrinol Nutr. 2012; 60(1):46-7. DOI: 10.1016/j.endonu.2012.01.021. View

Robert M, Belanger P, Simon Hould F, Marceau S, Tchernof A, Biertho L . Should metabolic surgery be offered in morbidly obese patients with type I diabetes?. Surg Obes Relat Dis. 2015; 11(4):798-805. DOI: 10.1016/j.soard.2014.12.016. View

Middelbeek R, James-Todd T, Patti M, Brown F . Short-term insulin requirements following gastric bypass surgery in severely obese women with type 1 diabetes. Obes Surg. 2014; 24(9):1442-6. PMC: 4122809. DOI: 10.1007/s11695-014-1228-8. View

Mendez C, Tanenberg R, Pories W . Outcomes of Roux-en-Y gastric bypass surgery for severely obese patients with type 1 diabetes: a case series report. Diabetes Metab Syndr Obes. 2011; 3:281-3. PMC: 3047955. View

Sarruf D, Bonner-Weir S, Schwartz M . New clues to bariatric surgery's benefits. Nat Med. 2012; 18(6):860-1. PMC: 3600352. DOI: 10.1038/nm.2801. View

Farilla L, Bulotta A, Hirshberg B, Li Calzi S, Khoury N, Noushmehr H . Glucagon-like peptide 1 inhibits cell apoptosis and improves glucose responsiveness of freshly isolated human islets. Endocrinology. 2003; 144(12):5149-58. DOI: 10.1210/en.2003-0323. View

10.

Polsky S, Ellis S . Obesity, insulin resistance, and type 1 diabetes mellitus. Curr Opin Endocrinol Diabetes Obes. 2015; 22(4):277-82. DOI: 10.1097/MED.0000000000000170. View

11.

Pozzilli P, Guglielmi C, Caprio S, Buzzetti R . Obesity, autoimmunity, and double diabetes in youth. Diabetes Care. 2011; 34 Suppl 2:S166-70. PMC: 3632156. DOI: 10.2337/dc11-s213. View

12.

Czupryniak L, Strzelczyk J, Cypryk K, Pawlowski M, Szymanski D, Lewinski A . Gastric bypass surgery in severely obese type 1 diabetic patients. Diabetes Care. 2004; 27(10):2561-2. DOI: 10.2337/diacare.27.10.2561. View

13.

Baskota A, Li S, Dhakal N, Liu G, Tian H . Bariatric Surgery for Type 2 Diabetes Mellitus in Patients with BMI <30 kg/m2: A Systematic Review and Meta-Analysis. PLoS One. 2015; 10(7):e0132335. PMC: 4500506. DOI: 10.1371/journal.pone.0132335. View

14.

Traina A, Lull M, Hui A, Zahorian T, Lyons-Patterson J . Once-weekly exenatide as adjunct treatment of type 1 diabetes mellitus in patients receiving continuous subcutaneous insulin infusion therapy. Can J Diabetes. 2014; 38(4):269-72. DOI: 10.1016/j.jcjd.2013.10.006. View

15.

Deitel M . Update: Why diabetes does not resolve in some patients after bariatric surgery. Obes Surg. 2010; 21(6):794-6. DOI: 10.1007/s11695-010-0329-2. View

16.

Raab H, Weiner R, Frenken M, Rett K, Weiner S . Obesity and metabolic surgery in type 1 diabetes mellitus. Nutr Hosp. 2013; 28 Suppl 2:31-4. DOI: 10.3305/nh.2013.28.sup2.6711. View

17.

Pozzilli P, Guglielmi C, Pronina E, Petraikina E . Double or hybrid diabetes associated with an increase in type 1 and type 2 diabetes in children and youths. Pediatr Diabetes. 2007; 8 Suppl 9:88-95. DOI: 10.1111/j.1399-5448.2007.00338.x. View

18.

Fourlanos S, Dotta F, Greenbaum C, Palmer J, Rolandsson O, Colman P . Latent autoimmune diabetes in adults (LADA) should be less latent. Diabetologia. 2005; 48(11):2206-12. DOI: 10.1007/s00125-005-1960-7. View

19.

Middelbeek R, James-Todd T, Cavallerano J, Schlossman D, Patti M, Brown F . Gastric Bypass Surgery in Severely Obese Women With Type 1 Diabetes: Anthropometric and Cardiometabolic Effects at 1 and 5 Years Postsurgery. Diabetes Care. 2015; 38(7):e104-5. PMC: 4876744. DOI: 10.2337/dc15-0396. View

20.

Shuai X, Tao K, Mori M, Kanda T . Bariatric surgery for metabolic syndrome in obesity. Metab Syndr Relat Disord. 2015; 13(4):149-60. DOI: 10.1089/met.2014.0115. View