A Systematic Review and Meta-Analysis of Outcomes for Type 1 Diabetes After Bariatric Surgery

Overview

Journal J Obes

Publisher Wiley

Specialty Endocrinology

Date 2016 Jul 5

PMID 27375900

Citations 15

Authors

Alexandra Chow

Noah J Switzer

Jerry Dang

Xinzhe Shi

Christopher de Gara

Daniel W Birch

Richdeep S Gill

Shahzeer Karmali

Affiliations

Soon will be listed here.

Abstract

Background. The utility of bariatric surgery in type 1 diabetes remains controversial. The aim of the present study is to evaluate glycemic control outcomes in obese patients with type 1 diabetes after bariatric surgery. Methods. A comprehensive search of electronic databases was completed. Inclusion criteria included human adult subjects with BMI ≥35 kg/m(2) and a confirmed diagnosis of type 1 diabetes who underwent a bariatric surgical procedure. Results. Thirteen primary studies (86 patients) were included. Subjects had a mean age of 41.16 ± 6.76 years with a mean BMI of 42.50 ± 2.65 kg/m(2). There was a marked reduction in BMI postoperatively at 12 months and at study endpoint to 29.55 ± 1.76 kg/m(2) (P < 0.00001) and 30.63 ± 2.09 kg/m(2) (P < 0.00001), respectively. Preoperative weighted mean total daily insulin requirement was 98 ± 26 IU/d, which decreased significantly to 36 ± 15 IU/d (P < 0.00001) and 42 ± 11 IU/d (P < 0.00001) at 12 months and at study endpoint, respectively. An improvement in HbA1c was also seen from 8.46 ± 0.78% preoperatively to 7.95 ± 0.55% (P = 0.01) and 8.13 ± 0.86% (P = 0.03) at 12 months and at study endpoint, respectively. Conclusion. Bariatric surgery in patients with type 1 diabetes leads to significant reductions in BMI and improvements in glycemic control.

Citing Articles

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Current status of metabolic surgery in patients with type I diabetes mellitus and obesity: a nationwide multicenter study.

Thaher O, Iaroshevych V, Driouch J, Hukauf M, Croner R, Stroh C Langenbecks Arch Surg. 2023; 408(1):46.

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Correlation between the Control of Blood Glucose Level and HbA1C and the Incidence of Surgical Site Infection after Emergent Surgery for the Lower Limb Fracture among Type II DM Patients Aged More Than 50 Years Old.

Wang W, Hsieh T, Wu W, Lee R, Wang J, Yeh K J Clin Med. 2022; 11(19).

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The impact of preoperative glycated hemoglobin (HbA1c) on postoperative complications after elective major abdominal surgery: a meta-analysis.

Wong J, Ke Y, Ong Y, Li H, Wong T, Abdullah H Korean J Anesthesiol. 2021; 75(1):47-60.

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Bariatric Surgery Outcomes in Patients with Latent Autoimmune Diabetes of the Adult.

Guimaraes M, Pereira S, Nora M, Monteiro M Obes Facts. 2021; 14(4):425-430.

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