Long-term Suicide Risk in No, One or More Mental Disorders: the Lundby Study 1947-1997
Overview
Authors
Affiliations
Objective: To investigate long-term suicide risk in individuals with no, one or more mental disorders.
Method: In the Lundby Study, involving a total population of 3563 subjects, mental health and suicide risk were monitored over 54-64 years.
Results: The long-term suicide risk in subjects with no, one, or more mental disorders was 0.3%, 3.4% and 6.2% respectively. For individuals with only depression, the risk was 6.0%, only alcohol use disorder 4.7%, and only psychosis 3.1%. However, when individuals had additional disorders, the suicide risks were 6.6%, 9.4% and 10.4% respectively. Each diagnosis per se was significantly related to increased risk of suicide. Men had a higher suicide risk in depression than women. Men who had alcohol use disorder in addition to depression showed a very high risk of suicide, 16.2%.
Conclusion: Long-term suicide risk was increased for depression, alcohol use disorder, and psychosis per se. For the latter two the diagnosis alone there may be a lower risk than previously estimated when there is no additional diagnosis. In men, depression in addition to alcohol use disorder should be treated vigorously in the work to prevent suicide.
Bornheimer L, Brdar N, Lapidos A, Kelter A, Miner C, Grogan-Kaylor A Early Interv Psychiatry. 2025; 19(2):e70013.
PMID: 39966957 PMC: 11836237. DOI: 10.1111/eip.70013.
Association of substance use with suicide mortality: An updated systematic review and meta-analysis.
Athey A, Shaff J, Kahn G, Brodie K, Ryan T, Sawyer H Drug Alcohol Depend Rep. 2025; 14:100310.
PMID: 39830682 PMC: 11741031. DOI: 10.1016/j.dadr.2024.100310.
Lange S, Kim K, Lasserre A, Orpana H, Bagge C, Roerecke M JAMA Netw Open. 2024; 7(3):e241941.
PMID: 38470417 PMC: 10933726. DOI: 10.1001/jamanetworkopen.2024.1941.
Machine learning and the prediction of suicide in psychiatric populations: a systematic review.
Pigoni A, Delvecchio G, Turtulici N, Madonna D, Pietrini P, Cecchetti L Transl Psychiatry. 2024; 14(1):140.
PMID: 38461283 PMC: 10925059. DOI: 10.1038/s41398-024-02852-9.
Keramatian K, Levit A J Can Acad Child Adolesc Psychiatry. 2023; 32(3):202-208.
PMID: 37534116 PMC: 10393356.