Diatom-Specific Oligosaccharide and Polysaccharide Structures Help to Unravel Biosynthetic Capabilities in Diatoms

Overview

Journal Mar Drugs

Publisher MDPI

Specialties Biology
Pharmacology

Date 2015 Sep 23

PMID 26393622

Citations 43

Authors

Bruno Gugi

Tinaig Le Costaouec

Carole Burel

Patrice Lerouge

William Helbert

Muriel Bardor

Affiliations

Soon will be listed here.

Abstract

Diatoms are marine organisms that represent one of the most important sources of biomass in the ocean, accounting for about 40% of marine primary production, and in the biosphere, contributing up to 20% of global CO₂ fixation. There has been a recent surge in developing the use of diatoms as a source of bioactive compounds in the food and cosmetic industries. In addition, the potential of diatoms such as Phaeodactylum tricornutum as cell factories for the production of biopharmaceuticals is currently under evaluation. These biotechnological applications require a comprehensive understanding of the sugar biosynthesis pathways that operate in diatoms. Here, we review diatom glycan and polysaccharide structures, thus revealing their sugar biosynthesis capabilities.

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