Technical Advances in Endoscopic Ultrasound-guided Fiducial Placement for the Treatment of Pancreatic Cancer

Overview

Journal Endosc Int Open

Specialty Gastroenterology

Date 2015 Sep 11

PMID 26355267

Citations 10

Authors

Disaya Chavalitdhamrong

Christopher J Dimaio

Peter D Siersema

Mihir S Wagh

Affiliations

Soon will be listed here.

Abstract

Radiation therapy has an important role in the treatment of locally advanced or metastatic pancreatic cancer and can be used alone or in conjunction with surgery and/or systemic chemotherapy. Because of the challenge of delivering an accurate and optimal radiation dose, image-guided radiation therapy can be used to improve targeting. Fiducial markers can be placed in the tumor and used for localization in patients undergoing image-guided radiation therapy. The safety and feasibility of endoscopic ultrasound (EUS)-guided placement of fiducials has been assessed and reported for the management of pancreatic cancer. We herein review the technique, efficacy, and safety profile of EUS-guided fiducial placement. In addition, we highlight recent advances and technological upgrades in EUS-guided fiducial delivery systems for pancreatic cancer most relevant to practicing gastroenterologists and interventional endoscopists.

Citing Articles

Endoscopic Ultrasound-Guided Fiducial Placement for Stereotactic Body Radiation Therapy in Pancreatic Malignancy.

Kim S, Shin E Clin Endosc. 2021; 54(3):314-323.

PMID: 34082487 PMC: 8182253. DOI: 10.5946/ce.2021.102.

GRUPUGE Perspective: Endoscopic Ultrasound-Guided Fine-Needle Tattooing and Fiducial Placement in Pancreatic Cancer.

Marques S, Bispo M, Leite S, Moreira T, Caldeira A, Moutinho-Ribeiro P GE Port J Gastroenterol. 2021; 28(2):106-110.

PMID: 33791397 PMC: 7991280. DOI: 10.1159/000509194.

EUS-guided placement of fiducial markers for image-guided radiotherapy in gastrointestinal tumors: A critical appraisal.

Carrara S, Rimbas M, Larghi A, Di Leo M, Comito T, Abi Jaoude J Endosc Ultrasound. 2021; 10(6):414-423.

PMID: 33666180 PMC: 8785666. DOI: 10.4103/EUS-D-20-00116.

and evaluation of the safety and efficacy of a novel liquid fiducial marker for image-guided radiotherapy.

Sun L, Su Y, Ding X, Xu D, Li C, Wang L Oncol Lett. 2020; 20(1):569-580.

PMID: 32565982 PMC: 7286123. DOI: 10.3892/ol.2020.11591.

EUS-guided fiducial placement for pancreatobiliary malignancies: safety, infection risk, and use of peri-procedural antibiotics.

Chandnani M, Faisal M, Glissen-Brown J, Sawhney M, Pleskow D, Cohen J Endosc Int Open. 2020; 8(2):E179-E185.

PMID: 32010751 PMC: 6976327. DOI: 10.1055/a-1068-9128.

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