Human Protein Interaction Networks Across Tissues and Diseases

Overview

Journal Front Genet

Date 2015 Sep 9

PMID 26347769

Citations 35

Authors

Esti Yeger-Lotem

Roded Sharan

Affiliations

Soon will be listed here.

Abstract

Protein interaction networks are an important framework for studying protein function, cellular processes, and genotype-to-phenotype relationships. While our view of the human interaction network is constantly expanding, less is known about networks that form in biologically important contexts such as within distinct tissues or in disease conditions. Here we review efforts to characterize these networks and to harness them to gain insights into the molecular mechanisms underlying human disease.

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