Perspective in Infertility: the Ovarian Stem Cells

Overview

Journal J Ovarian Res

Publisher Biomed Central

Specialties Gynecology & Obstetrics
Reproductive Medicine

Date 2015 Aug 8

PMID 26250560

Citations 20

Authors

Erica Silvestris

Stella DOronzo

Paola Cafforio

Giuseppe DAmato

Giuseppe Loverro

Affiliations

Soon will be listed here.

Abstract

Infertility is a medical and social condition that affects millions of women worldwide and is today considered so far as a new disease. A considerable progress has been recently pursued in the field of the reproductive medicine and the infertility treatment may account for novel and modern procedures such as in vitro oocyte fertilization, egg donation, pregnancy surrogacy and preimplantation diagnosis. However, great interest has lately been reserved to the ovarian stem cells (OSCs) whose existence in woman ovaries has been proven. OSCs are thus suitable for developmental studies in infertility and in other clinical applications as endocrine derangements due to premature ovarian failure, or for infertility treatment after cancer chemotherapies, as well as in restoring the hormonal balance in postmenopausal age.

Citing Articles

The Role of N6-methyladenosine Modification in Gametogenesis and Embryogenesis: Impact on Fertility.

Wang Y, Yang C, Sun H, Jiang H, Zhang P, Huang Y Genomics Proteomics Bioinformatics. 2024; 22(4).

PMID: 38937660 PMC: 11514847. DOI: 10.1093/gpbjnl/qzae050.

Pregnancy by Oocyte Donation: Reviewing Fetal-Maternal Risks and Complications.

Silvestris E, Petracca E, Mongelli M, Arezzo F, Loizzi V, Gaetani M Int J Mol Sci. 2023; 24(18).

PMID: 37762248 PMC: 10530596. DOI: 10.3390/ijms241813945.

Mesenchymal Stem Cells in Preclinical Infertility Cytotherapy: A Retrospective Review.

Chang Z, Zhu H, Zhou X, Zhang Y, Jiang B, Li S Stem Cells Int. 2021; 2021:8882368.

PMID: 34054970 PMC: 8143877. DOI: 10.1155/2021/8882368.

Estrogen regulation of germline stem cell differentiation as a mechanism contributing to female reproductive aging.

Satirapod C, Wang N, MacDonald J, Sun M, Woods D, Tilly J Aging (Albany NY). 2020; 12(8):7313-7333.

PMID: 32302290 PMC: 7202493. DOI: 10.18632/aging.103080.

Basal characterization and in vitro differentiation of putative stem cells derived from the adult mouse ovary.

Zolbin M, Sahin Ersoy G, Aliakbari F, Amidi F, Daghigh F, Abbasi M In Vitro Cell Dev Biol Anim. 2020; 56(1):59-66.

PMID: 31900800 DOI: 10.1007/s11626-019-00411-x.

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