An Interactive Database for the Assessment of Histone Antibody Specificity

Overview

Journal Mol Cell

Publisher Cell Press

Specialty Cell Biology

Date 2015 Jul 28

PMID 26212453

Citations 81

Authors

Scott B Rothbart

Bradley M Dickson

Jesse R Raab

Adrian T Grzybowski

Krzysztof Krajewski

Angela H Guo

Erin K Shanle

Steven Z Josefowicz

Stephen M Fuchs

C David Allis

Terry R Magnuson

Alexander J Ruthenburg

Brian D Strahl

Affiliations

Soon will be listed here.

Abstract

Access to high-quality antibodies is a necessity for the study of histones and their posttranslational modifications (PTMs). Here we debut the Histone Antibody Specificity Database (http://www.histoneantibodies.com), an online and expanding resource cataloging the behavior of widely used, commercially available histone antibodies by peptide microarray. This interactive web portal provides a critical resource to the biological research community that routinely uses these antibodies as detection reagents for a wide range of applications.

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