Bioactive Cembranoids from the South China Sea Soft Coral Sarcophyton Elegans

Overview

Journal Molecules

Publisher MDPI

Specialty Biology

Date 2015 Jul 25

PMID 26205057

Citations 9

Authors

Xin Liu

Junsheng Zhang

Qiao Liu

Guihua Tang

Hongsheng Wang

Chengqi Fan

Sheng Yin

Affiliations

Soon will be listed here.

Abstract

Four new cembranoids, sarcophelegans A-D (1-4) and six known analogues (5-10) were isolated from the South China Sea soft coral Sarcophyton elegans. Their structures were elucidated through detailed spectroscopic analysis, and the absolute conﬁguration of 1 was conﬁrmed by single-crystal X-ray diffraction. The antimigratory potential of compounds 1-10 were evaluated and compounds 2 and 6 were found to inhibit human breast tumor MDA-MB-231 cell migration at 10 μM.

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