Mesenchymal Hamartoma of the Liver in an Infant With Beckwith-Wiedemann Syndrome: A Rare Condition Mimicking Hepatoblastoma

Overview

Journal ACG Case Rep J

Specialty Gastroenterology

Date 2015 Jul 24

PMID 26203458

Citations 5

Authors

Lucas F Abrahao-Machado

Fabiane C de Macedo

Carlos Dalence

Glenn Stambo

Eduarda F Abrahao-Machado

Elaine C F Abrahao-Machado

Armita Bahrami

Antonio G Nascimento

Affiliations

Soon will be listed here.

Abstract

Patients with Beckwith-Wiedemann syndrome (BWS) are known to be at an increased risk for childhood malignancies, particularly Wilms tumor and hepatoblastoma. We report a case of genetically confirmed BWS in a 5-month-old girl who presented with a 9.5-cm abdominal mass associated with elevated α-fetoprotein levels. The clinical impression was strongly suggestive of hepatoblastoma. Histologic examination of the surgically excised mass revealed mesenchymal hamartoma of the liver (MHL), a benign hepatic neoplasm.

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