Embedded Online Questionnaire Measures Are Sensitive to Identifying Mild Cognitive Impairment

Overview

Journal Alzheimer Dis Assoc Disord

Specialties Neurology
Psychiatry

Date 2015 Jul 21

PMID 26191967

Citations 21

Authors

Adriana Seelye

Nora Mattek

Diane B Howieson

Daniel Austin

Katherine Wild

Hiroko H Dodge

Jeffrey A Kaye

Affiliations

Soon will be listed here.

Abstract

Background/aims: Early changes in cognitively demanding daily activities occur between normal cognition and the development of mild cognitive impairment (MCI). These real-world functional changes as early signals of cognitive change form a prime target for meaningful early detection of dementia. We examined whether passive aspects of responding to a remotely monitored weekly online questionnaire discriminated between older adults with and without MCI.

Methods: Participants were 83 independent, community-dwelling older adults enrolled in a longitudinal study of in-home monitoring technologies, which included completion of a short weekly online questionnaire of health and life events.

Results: In longitudinal analyses, time to complete the online questionnaire decreased over 1 year in both MCI and cognitively intact participants (P<0.01). MCI and intact participants did not differ in the time of day they submitted their questionnaires initially; however, over the course of 1 year MCI participants began to submit their questionnaires progressively later in the day and they needed greater assistance from staff as compared with intact participants (P<0.05). The online questionnaire performance measures were significantly correlated to conventional cognitive test scores (P<0.05) across the spectrum of normal cognition to MCI.

Conclusions: Ambiently assessed, passive performance measures embedded within an online questionnaire are able to discriminate between normal cognition and MCI. Remote monitoring of cognitively demanding routine daily activities is a promising approach for ecologically valid real-world cognitive assessment.

Citing Articles

Ascertaining Out-of-Pocket Costs of Dementia Care: Feasibility Study of a Web-Based Weekly Survey.

Dawson W, Mattek N, Gothard S, Kaye J, Lindauer A JMIR Form Res. 2024; 8:e56878.

PMID: 39321453 PMC: 11464940. DOI: 10.2196/56878.

Using Continuous Passive Assessment Technology to Describe Health and Behavior Patterns Preceding and Following a Cancer Diagnosis in Older Adults: Proof-of-Concept Case Series Study.

Wu C, Tibbitts D, Beattie Z, Dodge H, Shannon J, Kaye J JMIR Form Res. 2023; 7:e45693.

PMID: 37561574 PMC: 10450537. DOI: 10.2196/45693.

Correlating continuously captured home-based digital biomarkers of daily function with postmortem neurodegenerative neuropathology.

Hantke N, Kaye J, Mattek N, Wu C, Dodge H, Beattie Z PLoS One. 2023; 18(6):e0286812.

PMID: 37289845 PMC: 10249904. DOI: 10.1371/journal.pone.0286812.

Designing the next-generation clinical care pathway for Alzheimer's disease.

Hampel H, Au R, Mattke S, van der Flier W, Aisen P, Apostolova L Nat Aging. 2023; 2(8):692-703.

PMID: 37118137 PMC: 10148953. DOI: 10.1038/s43587-022-00269-x.

Olfactory function changes and the predictive performance of the Chinese Smell Identification Test in patients with mild cognitive impairment and Alzheimer's disease.

Mi Y, Ma X, Du S, Du C, Li X, Tan H Front Aging Neurosci. 2023; 15:1068708.

PMID: 36861124 PMC: 9969891. DOI: 10.3389/fnagi.2023.1068708.

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