THz Medical Imaging: Hydration Sensing

Overview

Journal IEEE Trans Terahertz Sci Technol

Date 2015 Jun 19

PMID 26085958

Citations 45

Authors

Zachary D Taylor

Rahul S Singh

David B Bennett

Priyamvada Tewari

Colin P Kealey

Neha Bajwa

Martin O Culjat

Alexander Stojadinovic

Hua Lee

Jean-Pierre Hubschman

Elliott R Brown

Warren S Grundfest

Affiliations

Soon will be listed here.

Abstract

The application of THz to medical imaging is experiencing a surge in both interest and federal funding. A brief overview of the field is provided along with promising and emerging applications and ongoing research. THz imaging phenomenology is discussed and tradeoffs are identified. A THz medical imaging system, operating at ~525 GHz center frequency with ~125 GHz of response normalized bandwidth is introduced and details regarding principles of operation are provided. Two promising medical applications of THz imaging are presented: skin burns and cornea. For burns, images of second degree, partial thickness burns were obtained in rat models over an 8 hour period. These images clearly show the formation and progression of edema in and around the burn wound area. For cornea, experimental data measuring the hydration of porcine cornea under drying is presented demonstrating utility in ophthalmologic applications.

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