Bone Density and Fractures in HIV-infected Postmenopausal Women: A Systematic Review

Overview

Journal J Assoc Nurses AIDS Care

Specialties Infectious Diseases
Nursing

Date 2015 Jun 13

PMID 26066693

Citations 12

Authors

Yamnia I Cortes

Michael T Yin

Nancy K Reame

Affiliations

Soon will be listed here.

Abstract

With the development of effective antiretroviral therapy, HIV-infected women are living longer and transitioning through menopause. The purpose of our study was to systematically examine the evidence that menopause is an additional risk predictor for osteoporosis and fractures in HIV-infected women. Electronic databases were searched for studies of low bone density or fractures in HIV-infected postmenopausal women. Studies that met the inclusion criteria (n = 10) were appraised using a validated quality assessment tool. The majority of studies were rated as good quality and the remaining were fair. The prevalence of osteoporosis reported in these studies ranged from 7.3% to 84% and 0.7% to 23% in HIV-infected and uninfected postmenopausal women, respectively. In the two qualifying studies, postmenopausal status was not a predictor of fractures in HIV-infected women. Findings suggest that HIV care providers should accurately assess postmenopausal status and modifiable risk factors for osteoporosis in all older HIV-infected women.

Citing Articles

Evaluation of bone mineral density and its influencing factors in patients infected with HIV under antiretroviral therapy.

Azarboo A, Hemmatabadi M, Fahimfar N, Faghihi Z, SeyedAlinaghi S, Shirzad N BMC Infect Dis. 2025; 25(1):33.

PMID: 39762767 PMC: 11706035. DOI: 10.1186/s12879-024-10388-y.

Bone Loss and Fractures in Post-Menopausal Women Living with HIV: A Narrative Review.

Jamshaid M, Heidari A, Hassan A, Mital D, Pearce O, Panourgia M Pathogens. 2024; 13(9).

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Bone Tissue Changes in Individuals Living with HIV/AIDS: The Importance of a Hierarchical Approach in Investigating Bone Fragility.

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Prevalence of and risk factors for vertebral fracture and low bone mineral density among Peruvian women aging with HIV.

Cabrera D, Cornejo M, Slotkin R, Pinedo Y, Yu W, Guan W Arch Osteoporos. 2023; 18(1):64.

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Menopause care in women living with HIV in the UK - A review.

Dragovic B, Rymer J, Nwokolo N J Virus Erad. 2022; 8(1):100064.

PMID: 35242357 PMC: 8866072. DOI: 10.1016/j.jve.2022.100064.

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