» Articles » PMID: 26041961

Magnetic Resonance Imaging and Spectroscopy in Hepatic Encephalopathy

Overview
Publisher Elsevier
Specialty Gastroenterology
Date 2015 Jun 5
PMID 26041961
Citations 13
Authors
Affiliations
Soon will be listed here.
Abstract

Hepatic encephalopathy is a brain alteration associated to liver failure that produces cognitive impairments at long term. Neuroimaging are non-invasive methods for the study of the brain by means of spectroscopy and imaging techniques. These technologies give huge information about cerebral metabolism and water distribution to explore brain pathways involved in the pathogenesis of hepatic encephalopathy. Furthermore, new magnetic resonance implementations such as voxel-based morphometry or resting-state functional magnetic resonance imaging allow studying brain atrophy and neuronal connectivity of the cerebral network involved in the neurocognitive impairments observed in the patients. The development of magnetic resonance technology will generate handy tools for the brain study of liver failure to elucidate the time-course of the pathology and thus to obtain an early diagnosis of cerebral complications.

Citing Articles

Multiple ammonia-induced episodes of hepatic encephalopathy provoke neuronal cell loss in bile-duct ligated rats.

Tamnanloo F, Ochoa-Sanchez R, Oliveira M, Lima C, Lepine M, Dubois K JHEP Rep. 2023; 5(12):100904.

PMID: 37942225 PMC: 10628859. DOI: 10.1016/j.jhepr.2023.100904.


Regulation of mild cognitive impairment associated with liver disease by humoral factors derived from the gastrointestinal tract and MRI research progress: a literature review.

Sun T, Feng M, Manyande A, Xiang H, Xiong J, He Z Front Neurosci. 2023; 17:1206417.

PMID: 37397455 PMC: 10312011. DOI: 10.3389/fnins.2023.1206417.


Neurological Wilson's Disease Signs-Hepatic Encephalopathy or Copper Toxicosis?.

Jopowicz A, Tarnacka B Diagnostics (Basel). 2023; 13(5).

PMID: 36900037 PMC: 10001333. DOI: 10.3390/diagnostics13050893.


The neurogliovascular unit in hepatic encephalopathy.

Claeys W, Van Hoecke L, Lefere S, Geerts A, Verhelst X, Van Vlierberghe H JHEP Rep. 2021; 3(5):100352.

PMID: 34611619 PMC: 8476774. DOI: 10.1016/j.jhepr.2021.100352.


Copper, Iron, and Manganese Toxicity in Neuropsychiatric Conditions.

Tarnacka B, Jopowicz A, Maslinska M Int J Mol Sci. 2021; 22(15).

PMID: 34360586 PMC: 8346158. DOI: 10.3390/ijms22157820.


References
1.
Hassanein T, Blei A, Perry W, Hilsabeck R, Stange J, Larsen F . Performance of the hepatic encephalopathy scoring algorithm in a clinical trial of patients with cirrhosis and severe hepatic encephalopathy. Am J Gastroenterol. 2009; 104(6):1392-400. DOI: 10.1038/ajg.2009.160. View

2.
Saksena S, Rai V, Saraswat V, Rathore R, Purwar A, Kumar M . Cerebral diffusion tensor imaging and in vivo proton magnetic resonance spectroscopy in patients with fulminant hepatic failure. J Gastroenterol Hepatol. 2007; 23(7 Pt 2):e111-9. DOI: 10.1111/j.1440-1746.2007.05158.x. View

3.
Chen H, Zhu X, Shu H, Yang M, Zhang Y, Ding J . Structural and functional cerebral impairments in cirrhotic patients with a history of overt hepatic encephalopathy. Eur J Radiol. 2011; 81(10):2463-9. DOI: 10.1016/j.ejrad.2011.10.008. View

4.
Tarasow E, Panasiuk A, Siergiejczyk L, Orzechowska-Bobkiewicz A, Lewszuk A, Walecki J . MR and 1H MR spectroscopy of the brain in patients with liver cirrhosis and early stages of hepatic encephalopathy. Hepatogastroenterology. 2003; 50(54):2149-53. View

5.
Le Bihan D, Mangin J, Poupon C, Clark C, Pappata S, Molko N . Diffusion tensor imaging: concepts and applications. J Magn Reson Imaging. 2001; 13(4):534-46. DOI: 10.1002/jmri.1076. View