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The Utility of Ultrasonographic Bone Age Determination in Detecting Growth Disturbances; a Comparative Study with the Conventional Radiographic Technique

Overview
Journal Skeletal Radiol
Specialties Orthopedics
Radiology
Date 2015 May 31
PMID 26025121
Citations 3
Authors
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Abstract

Objective: To test whether the conventional radiographic technique in determining bone age abnormalities can be replaced by ultrasonography.

Materials And Methods: A total of 54 Caucasian subjects up to 7 years of age with clinically suspected growth problems underwent left hand and wrist radiographic and ultrasonographic bone age estimations with the use of the Greulich-Pyle atlas. The ultrasonographic scans targeted the ossification centers in the radius and ulna distal epiphysis, carpal bones, epiphyses of the first and third metacarpals, and epiphysis of the middle phalanx, as described in previous reports. The degree of agreement between the two sets of data, as well as the accuracy of the ultrasonographic method in detecting radiographically suggested bone age abnormities, was examined.

Results: The mean chronological age, radiographic bone age, and ultrasonographic bone age (all in months) were 41.96 ± 22.25, 26.68 ± 14.08, and 26.71 ± 13.50 in 28 boys and 43.62 ± 24.63, 30.12 ± 17.69, and 31.27 ± 18.06 in 26 girls, respectively. According to the Bland-Altman plot there was high agreement between the results of the two methods with only three outliers. The deviations in bone age from the chronological age taken by the two techniques had the same sign in all patients. Supposing radiography to be the method of reference, the sensitivity, specificity, positive predictive value, and negative predictive value of sonography in detecting growth abnormalities were all 100% in males and 90.9, 100, 100, and 93.8%, respectively, in females.

Conclusion: The conventional radiographic technique for determining bone age abnormalities could be replaced by ultrasonography.

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References
1.
Buken B, Safak A, Yazici B, Buken E, Mayda A . Is the assessment of bone age by the Greulich-Pyle method reliable at forensic age estimation for Turkish children?. Forensic Sci Int. 2007; 173(2-3):146-53. DOI: 10.1016/j.forsciint.2007.02.023. View

2.
Horter M, Friesen S, Wacker S, Vogt B, Leidiger B, Roedl R . [Determination of skeletal age : comparison of the methods of Greulich and Pyle and Tanner and Whitehouse]. Orthopade. 2012; 41(12):966-76. DOI: 10.1007/s00132-012-1983-y. View

3.
Wagner U, Diedrich V, Schmitt O . Determination of skeletal maturity by ultrasound: a preliminary report. Skeletal Radiol. 1995; 24(6):417-20. DOI: 10.1007/BF00941236. View

4.
Koc A, Karaoglanoglu M, Erdogan M, Kosecik M, Cesur Y . Assessment of bone ages: is the Greulich-Pyle method sufficient for Turkish boys?. Pediatr Int. 2001; 43(6):662-5. DOI: 10.1046/j.1442-200x.2001.01470.x. View

5.
Zhang A, Sayre J, Vachon L, Liu B, Huang H . Racial differences in growth patterns of children assessed on the basis of bone age. Radiology. 2008; 250(1):228-35. PMC: 2817832. DOI: 10.1148/radiol.2493080468. View