Assessing Breast Tumor Margin by Multispectral Photoacoustic Tomography

Overview

Journal Biomed Opt Express

Specialty Radiology

Date 2015 Apr 25

PMID 25909011

Citations 45

Authors

Rui Li

Pu Wang

Lu Lan

Frank P Lloyd Jr

Craig J Goergen

Shaoxiong Chen

Ji-Xin Cheng

Affiliations

Soon will be listed here.

Abstract

An unmet need exists in high-speed and highly-sensitive intraoperative assessment of breast cancer margin during conservation surgical procedures. Here, we demonstrate a multispectral photoacoustic tomography system for breast tumor margin assessment using fat and hemoglobin as contrasts. This system provides ~3 mm tissue depth and ~125 μm axial resolution. The results agreed with the histological findings. A high sensitivity in margin assessment was accomplished, which opens a compelling way to intraoperative margin assessment.

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