Seroprevalence of Toxoplasma Gondii Infections in Pregnant Women in Gorgan City, Golestan Province, Northern Iran-2012

Overview

Journal Iran J Parasitol

Publisher Tehran University of Medical Sciences

Specialty Parasitology

Date 2015 Apr 8

PMID 25848383

Citations 13

Authors

Mitra Sharbatkhori

Yusef Dadi Moghaddam

Abdol Sattar Pagheh

Rasool Mohammadi

Haleh Hedayat Mofidi

Saeedeh Shojaee

Affiliations

Soon will be listed here.

Abstract

Background: Toxoplasma gondii is one of the most prevalent parasites of human and warm- blooded animals. Toxoplasmosis is important especially in two groups: pregnant women and immunocompromised patients. If women acquire the primary infection during the pregnancy, it would be life threatening or remains severe disorders for the fetus. This study was performed to evaluate the seroprevalence of T. gondii infection in pregnant women referred to Health Center in Gorgan City, Golestan Province, northern Iran.

Methods: Serum samples were collected from pregnant women referred to Health Center in Gorgan City, south eastern Caspian Sea. Anti- Toxoplasma IgG and IgM antibodies were determined by commercially ELISA kits and the relation of infection with socio-demographic and risk factors such as age, education, occupation, cat ownership, soil contact and some other factors was studied.

Results: From 555 tested sera of pregnant women referred to Health Center in Gorgan, 39.8% had IgG antibodies against T. gondii and 3.4% were positive for IgM antibodies. A significant correlation was seen between T. gondii infection with age and soil contact.

Conclusion: About 60% of pregnant women in Gorgan City are seronegative against T. gondii, so they should considered as at risk persons.

Citing Articles

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Seromolecular study on the prevalence and risk factors of Toxoplasma gondii infection in pregnant women referred to a gynecology hospital in Urmia, northwest part of Iran in 2022.

Bashour N, Aminpour A, Vazifehkhah S, Jafari R BMC Infect Dis. 2024; 24(1):410.

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Prevalence and risk factors of Toxoplasma gondii infection among women with miscarriage and their aborted fetuses in the northwest of Iran.

Zeinali S, Khademvatan S, Jafari R, Vazifekhah S, Yousefi E, Behroozi-Lak T PLoS One. 2023; 18(10):e0283493.

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Seroepidemiological study of toxoplasmosis in women referred to a pre-marriage counseling center in Alborz Province, Iran.

Shahighi M, Heidari A, Keshavarz H, Bairami A, Shojaee S, Sezavar M BMC Res Notes. 2021; 14(1):163.

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Occurrence of antibodies and associated risk factors in women in selected districts of Punjab province, Pakistan.

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References

Alvarado-Esquivel C, Torres-Castorena A, Liesenfeld O, Garcia-Lopez C, Estrada-Martinez S, Sifuentes-Alvarez A . Seroepidemiology of Toxoplasma gondii infection in pregnant women in rural Durango, Mexico. J Parasitol. 2008; 95(2):271-4. DOI: 10.1645/GE-1829.1. View

Hajsoleimani F, Ataeian A, Nourian A, Mazloomzadeh S . Seroprevalence of Toxoplasma gondii in Pregnant Women and Bioassay of IgM Positive Cases in Zanjan, Northwest of Iran. Iran J Parasitol. 2012; 7(2):82-6. PMC: 3469192. View

Boyle J, Radke J . A history of studies that examine the interactions of Toxoplasma with its host cell: Emphasis on in vitro models. Int J Parasitol. 2009; 39(8):903-14. DOI: 10.1016/j.ijpara.2009.01.008. View

Speer C, Dubey J . Ultrastructural differentiation of Toxoplasma gondii schizonts (types B to E) and gamonts in the intestines of cats fed bradyzoites. Int J Parasitol. 2005; 35(2):193-206. DOI: 10.1016/j.ijpara.2004.11.005. View

Studenicova C, Ondriska F, Holkova R . [Seroprevalence of Toxoplasma gondii among pregnant women in Slovakia]. Epidemiol Mikrobiol Imunol. 2008; 57(1):8-13. View

Montoya J, Liesenfeld O . Toxoplasmosis. Lancet. 2004; 363(9425):1965-76. DOI: 10.1016/S0140-6736(04)16412-X. View

Al-Mohammad H, Amin T, Balaha M, Al-Moghannum M . Toxoplasmosis among the pregnant women attending a Saudi maternity hospital: seroprevalence and possible risk factors. Ann Trop Med Parasitol. 2010; 104(6):493-504. DOI: 10.1179/136485910X12786389891443. View

Remington J, Thulliez P, Montoya J . Recent developments for diagnosis of toxoplasmosis. J Clin Microbiol. 2004; 42(3):941-5. PMC: 356902. DOI: 10.1128/JCM.42.3.941-945.2004. View

Weiss L, Dubey J . Toxoplasmosis: A history of clinical observations. Int J Parasitol. 2009; 39(8):895-901. PMC: 2704023. DOI: 10.1016/j.ijpara.2009.02.004. View

10.

Dubey J . The history of Toxoplasma gondii--the first 100 years. J Eukaryot Microbiol. 2009; 55(6):467-75. DOI: 10.1111/j.1550-7408.2008.00345.x. View

11.

Fuente M, Bovone N, Cabral G . [Prophylaxis of prenatal toxoplasmosis]. Medicina (B Aires). 1997; 57(2):155-60. View

12.

Akyar I . Seroprevalence and Coinfections of Toxoplasma gondii in Childbearing Age Women in Turkey. Iran J Public Health. 2012; 40(1):63-7. PMC: 3481714. View

13.

Tenter A, Heckeroth A, Weiss L . Toxoplasma gondii: from animals to humans. Int J Parasitol. 2000; 30(12-13):1217-58. PMC: 3109627. DOI: 10.1016/s0020-7519(00)00124-7. View

14.

Saeedi M, Veghari G, Marjani A . Seroepidemiologic evaluation of anti-toxoplasma antibodies among women in north of Iran. Pak J Biol Sci. 2008; 10(14):2359-62. DOI: 10.3923/pjbs.2007.2359.2362. View

15.

Aspock H, Pollak A . Prevention of prenatal toxoplasmosis by serological screening of pregnant women in Austria. Scand J Infect Dis Suppl. 1992; 84:32-7. View

16.

Fallah M, Rabiee S, Matini M, Taherkhani H . Seroepidemiology of toxoplasmosis in primigravida women in Hamadan, Islamic Republic of Iran, 2004. East Mediterr Health J. 2008; 14(1):163-71. View

17.

Ghorbani M, Edrissian G, Assad N . Serological survey of toxoplasmosis in the northern part of Iran, using indirect fluorescent antibody technique. Trans R Soc Trop Med Hyg. 1978; 72(4):369-71. DOI: 10.1016/0035-9203(78)90129-3. View

18.

Jaqueti J, Hernandez-Garcia R, Nicolas D, Martinez-Hernandez D . [Serology against Toxoplasma gondii in pregnant women. Development of prevalence rates in the course of 4 years]. Rev Clin Esp. 1991; 188(6):278-80. View

19.

Ayi I, Edu S, Apea-Kubi K, Boamah D, Bosompem K, Edoh D . Sero-epidemiology of toxoplasmosis amongst pregnant women in the greater accra region of ghana. Ghana Med J. 2010; 43(3):107-14. PMC: 2810244. DOI: 10.4314/gmj.v43i3.55325. View