Six Challenges in the Eradication of Infectious Diseases

Overview

Journal Epidemics

Publisher Elsevier

Specialties Infectious Diseases
Public Health

Date 2015 Apr 7

PMID 25843393

Citations 22

Authors

Petra Klepac

Sebastian Funk

T Deirdre Hollingsworth

C Jessica E Metcalf

Katie Hampson

Affiliations

Soon will be listed here.

Abstract

Eradication and elimination are increasingly a part of the global health agenda. Once control measures have driven infection to low levels, the ecology of disease may change posing challenges for eradication efforts. These challenges vary from identifying pockets of susceptibles, improving monitoring during and after the endgame, to quantifying the economics of disease eradication versus sustained control, all of which are shaped and influenced by processes of loss of immunity, susceptible build-up, emergence of resistance, population heterogeneities and non-compliance with control measures. Here we discuss how modelling can be used to address these challenges.

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