New Septanoside and 20-hydroxyecdysone Septanoside Derivative from Atriplex Portulacoides Roots with Preliminary Biological Activities

Overview

Journal Bioorg Med Chem Lett

Specialty Biochemistry

Date 2015 Mar 28

PMID 25813159

Citations 11

Authors

Aymen Ben Nejma

Asma Nguir

Hichem Ben Jannet

Mhamed Ali Hamza

Adam Daich

Mohamed Othman

Ata Martin Lawson

Affiliations

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Abstract

The phytochemical investigation of a Tunisian plant Atriplex portulacoides (Chenopodiaceae) led to the isolation of two new compounds designated as portulasoid (2) and septanoecdysone (3) along with the known 20-hydroxyecdysone (20HE) (1). Their chemical structures were elucidated on the basis of extensive spectroscopic methods including ES-HRMS, 1D and 2D-NMR. The isolated compounds were finally tested for their antioxidant activity by using DPPH, ABTS(+), Fe(3+) and catalase assays and also for their antibacterial and anticholinesterase activities.

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