Genealogical Histories in Structured Populations

Overview

Journal Theor Popul Biol

Specialties Biology
Genetics
Reproductive Medicine

Date 2015 Mar 16

PMID 25770971

Citations 3

Authors

Seiji Kumagai

Marcy K Uyenoyama

Affiliations

Soon will be listed here.

Abstract

In genealogies of genes sampled from structured populations, lineages coalesce at rates dependent on the states of the lineages. For migration and coalescence events occurring on comparable time scales, for example, only lineages residing in the same deme of a geographically subdivided population can have descended from a common ancestor in the immediately preceding generation. Here, we explore aspects of genealogical structure in a population comprising two demes, between which migration may occur. We use generating functions to obtain exact densities and moments of coalescence time, number of mutations, total tree length, and age of the most recent common ancestor of the sample. We describe qualitative features of the distribution of gene genealogies, including factors that influence the geographical location of the most recent common ancestor and departures of the distribution of internode lengths from exponential.

Citing Articles

Joint identity among loci under mutation and regular inbreeding.

Uyenoyama M Theor Popul Biol. 2024; 159:74-90.

PMID: 39208993 PMC: 11495244. DOI: 10.1016/j.tpb.2024.08.002.

Inductive determination of allele frequency spectrum probabilities in structured populations.

Uyenoyama M, Takebayashi N, Kumagai S Theor Popul Biol. 2019; 129:148-159.

PMID: 30641073 PMC: 6836295. DOI: 10.1016/j.tpb.2018.10.004.

Ancestry Testing and the Practice of Genetic Counseling.

Kirkpatrick B, Rashkin M J Genet Couns. 2016; 26(1):6-20.

PMID: 27704392 DOI: 10.1007/s10897-016-0014-2.

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